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GRM2 wt Allele

Known as: Glutamate Receptor, Metabotropic 2 wt Allele, GLUR2, GPRC1B 
Human GRM2 wild-type allele is located in the vicinity of 3p21.2 and is approximately 12 kb in length. This allele, which encodes metabotropic… 
National Institutes of Health

Related topics

Related topics

6 relations
3p21.2G Protein-Coupled Receptor SignalingLigand BindingReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
QSAR design of triazolopyridine mGlu2 receptor positive allosteric modulators.
Review
2013
Review
2013
mGluR2 positive allosteric modulators: a patent review (2009 – present)
Introduction: The mGlu2 receptor, which belongs to the group II subfamily of metabotropic glutamate receptors (mGlu) along with… 
2013
2013
Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice
BackgroundGroup II metabotropic glutamate receptors (mGlu2 and mGlu3, encoded by Grm2 and Grm3) have been the focus of attention… 
2011
2011
Study of Novel Selective mGlu2 Agonist in the Temporo-Ammonic Input to CA1 Neurons Reveals Reduced mGlu2 Receptor Expression in a Wistar Substrain with an Anxiety-Like Phenotype
Group II metabotropic receptors (mGluRs) regulate central synaptic transmission by modulating neurotransmitter release. However… 
2010
2010
Activation of metabotropic glutamate (mGlu)2 receptors suppresses histamine release in limbic brain regions following acute ketamine challenge
2005
2005
Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators.
2005
2005
Binding of 5'-GMP to the GluR2 AMPA receptor: insight from targeted molecular dynamics simulations.
Guanine nucleotides behave as competitive antagonists at ionotropic glutamate receptors and show neuroprotective activity in… 
2003
2003
Synthesis and structure-activity relationship studies of novel 2-diarylethyl substituted (2-carboxycycloprop-1-yl)glycines as high-affinity group II metabotropic glutamate receptor ligands.
2003
2003
Structural Model of the N-Methyl-D-aspartate Receptor Glycine Site Probed by Site-directed Chemical Coupling*
The N-methyl-d-aspartate (NMDA) receptor is a ligand-gated ion channel that requires both glutamate and glycine for efficient… 
2002
2002
Modulation of stress-induced and stimulated hyperprolactinemia with the group II metabotropic glutamate receptor selective agonist, LY379268
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