Skip to search formSkip to main contentSkip to account menu

GCLM gene

Known as: GCLM, GLUTAMATE-CYSTEINE LIGASE, REGULATORY, gamma-glutamylcysteine synthetase 
This gene is involved in the detoxification of endogenous reactive oxygen species. It also plays a role in drug and xenobiotic metabolism.
National Institutes of Health

Related topics

Related topics

7 relations
GCLC protein, humanGCLM protein, humanGlutamate-Cysteine LigaseMetabolic Detoxication, Drug

Narrower (1)

GCLM wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
This information is current as Human T Lymphocytes Therapeutic NRF 2 Activation in Primary Editing Using CRISPR / Cas 9 for KEAP 1 Hamad
2017
2017
Gastric Cancer with Liver Metastasis (GCLM) and the Importance of Dormant Cancer Stem Cells
Surgical treatment of gastric cancer with liver metastasis (GCLM) is even more interested for oncologists. Liver resection or RFA… 
2015
2015
Polymorphisms in Antioxidant Genes GCLM and GPX-4 and Ischemic Heart Disease Development in Kazakhstan Population
Background: This study investigated whether the main antioxidant genes GCLM and GPX4 single nucleotide polymorphisms are… 
2014
2014
[Study on anti-oxidative effect of extracts from Cichorium endivia on HepG2 cells and its mechanism].
OBJECTIVE To investigate the protective effect of extracts from Cichorium endivia (CEE) in H2O2-induced HepG2 cell oxidative… 
2012
2012
Inhalation of Diesel Exhaust (DE) and its effects on inflammation and vascular function; investigating the role of oxidative stress and glutathione in DE-mediated effects
Inhalation of Diesel Exhaust (DE) and its effects on inflammation and vascular function; investigating the role of oxidative… 
2010
2010
Developmental in vivo 1H NMR spectroscopy at 14.1 T in mice with genetic redox dysregulation: an animal model with relevance to schizophrenia
Keywords: CIBM-AIT Reference EPFL-CONF-177627 Record created on 2012-05-29, modified on 2016-08-09 
2009
2009
Association and expression studies of glutamate-cysteine ligase modifier (GCLM) and schizophrenia in the Chinese Han population.
Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai… 
2006
2006
GCLM C-588T多态与中国人冠状动脉粥样硬化性心脏病遗传易感性的关系
目的 探讨谷氨酸-半胱氨酸连接酶修饰亚单位基因（glutarnat-cysteine ligase modifier subunit gene，GCLM）C-588T多态与中国人冠状动脉粥样硬化性心脏病（coronary heart disease，CHD… 
2006
2006
Association of GCLM C-588T Polymorphism with Genetic Susceptibility to Coronary Heart Disease in Chinese Population
Objective To investigate the possible association of the glutamate-cysteine ligase modifier subunit gene(GCLM) C-588T… 
1978
1978
The reluctant President : the memoirs of the Hon. Clifford Dupont, GCLM., ID.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)