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Fludarabine phosphate

Known as: F-ara-AMP, fludarabine phosphate [Chemical/Ingredient], 2-F-ara-AMP 
The phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity… 
National Institutes of Health

Related topics

Related topics

28 relations
2 ML Fludarabine phosphate 25 MG/ML InjectionBeneflurChronic Lymphocytic LeukemiaDNA Polymerase I

Broader (4)

Antimetabolites, AntineoplasticImmunosuppressive AgentsVidarabine Phosphatefludarabine

Narrower (1)

NSC 312887

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains
ABSTRACT PPI-0903M is a novel N-phosphono-type cephalosporin active against oxacillin-resistant staphylococci and many other gram… 
Highly Cited
2004
Highly Cited
2004
Characterization of a Gemcitabine-Resistant Murine Leukemic Cell Line
Resistance to cytotoxic nucleoside analogues is a major problem in cancer treatment. The cellular mechanisms involved in this… 
Highly Cited
2000
Highly Cited
2000
XIAP Regulates DNA Damage-induced Apoptosis Downstream of Caspase-9 Cleavage*
The IAP (inhibitor ofapoptosis) family of anti-apoptotic proteins regulates programmed cell death. Of the six known human IAP… 
Highly Cited
1993
Highly Cited
1993
Synaptic Density of Axotomized Hypoglossal Motorneurons Following Pharmacological Blockade of the Microglial Cell Proliferation
The purpose of the present study was to examine the possible role of reactive microglia in the removal of presynaptic terminals… 
Review
1990
Review
1990
Metabolism and action of fludarabine phosphate.
Fludara I.V. (fludarabine phosphate) (9-beta-D-arabinosyl-2-fluoroadenine, F-ara-A) is an adenine nucleoside analogue resistant… 
Highly Cited
1988
Highly Cited
1988
Modulation of arabinosylnucleoside metabolism by arabinosylnucleotides in human leukemia cells.
Previous studies have indicated that deoxycytidine kinase (dCK) is requisite and rate limiting in the phosphorylation of 1-beta-D… 
Review
1986
Review
1986
Central nervous system toxicity of fludarabine phosphate.
: Fourteen patients developed severe central nervous system (CNS) toxicity after receiving an investigational antitumor agent… 
Highly Cited
1983
Highly Cited
1983
Oriented axon outgrowth from avian embryonic retinae in culture.
Highly Cited
1981
Highly Cited
1981
Identification of the mechanism of activation of 9-beta-D-arabinofuranosyladenine in human lymphoid cells using mutants deficient in nucleoside kinases.
The biochemical basis of cellular resistance to 9-beta-D-arabinofuranosyladenine (ara-A) and its natural purine derivative… 
Highly Cited
1975
Highly Cited
1975
Mode of action of 9-beta-D-arabinofuranosyladenine on the synthesis of DNA, RNA, and protein in vivo and in vitro.
The influence of 9-beta-D-arabinofuranosyladenine (ara-A) and its 5'-triphosphate derivative on programmed synthesis was tested… 
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