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fludarabine

Known as: fludarabine [Chemical/Ingredient], 2-fluoroadenine arabinoside, 9-Beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine 
A fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Administered parenterally as a… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
In October 2017, the FDA granted regular approval to axicabtagene ciloleucel, a CD19-directed chimeric antigen receptor (CAR) T… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND On the basis of promising results that were reported in several phase 2 trials, we investigated whether the addition… Expand
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Highly Cited
2010
Highly Cited
2010
PURPOSE Rituximab, a monoclonal antibody that targets the CD20 cell surface antigen, has clinical activity in patients with non… Expand
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Highly Cited
2008
Highly Cited
2008
Early results of the fludarabine, cyclophosphamide, and rituximab (FCR) regimen in 224 patients showed that it was highly active… Expand
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Highly Cited
2007
Highly Cited
2007
Autophagy is an intracellular bulk degradation process for proteins and organelles. In the heart, autophagy is stimulated by… Expand
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Highly Cited
2006
Highly Cited
2006
Combination chemotherapy with fludarabine plus cyclophosphamide (FC) was compared with the standard regimen of fludarabine… Expand
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Highly Cited
2005
Highly Cited
2005
PURPOSE Fludarabine and cyclophosphamide (FC), which are active in treatment of chronic lymphocytic leukemia (CLL), are… Expand
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Highly Cited
2005
Highly Cited
2005
PURPOSE The efficacy, toxicity, and tolerability of chemoimmunotherapy with the combination of fludarabine, cyclophosphamide, and… Expand
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Highly Cited
2002
Highly Cited
2002
This study investigated the efficacy, safety, and clinical benefit of alemtuzumab (Campath-1H) for patients with relapsed or… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Fludarabine is an effective treatment for chronic lymphocytic leukemia that does not respond to initial treatment with… Expand
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