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fludarabine

Known as: fludarabine [Chemical/Ingredient], 2-fluoroadenine arabinoside, 9-Beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine 
A fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Administered parenterally as a… 
National Institutes of Health

Related topics

Related topics

27 relations
2 ML Fludarabine phosphate 25 MG/ML InjectionChronic Lymphocytic LeukemiaDrug AllergyFCR Regimen

Broader (4)

Antineoplastic AgentsNucleoside AnalogsVidarabineadenine nucleoside

Narrower (1)

Fludarabine phosphate

Papers overview

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Review
2005
Review
2005
The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute myeloid leukemia in children: an evidence-based review.
Highly Cited
2004
Highly Cited
2004
Prophylaxis with defibrotide prevents veno-occlusive disease in stem cell transplantation after gemtuzumab ozogamicin exposure.
Gemtuzumab ozogamicin (GO; Mylotarg; Wyeth, PA) is a humanized anti-CD33 antibody conjugated to the cytotoxic agent calicheamicin… 
Highly Cited
2003
Highly Cited
2003
Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy.
Highly Cited
1998
Highly Cited
1998
Triggering of CD40 Antigen Inhibits Fludarabine-Induced Apoptosis in B Chronic Lymphocytic Leukemia Cells
We analyzed the effect of CD40 triggering on the fludarabine-induced apoptosis of B chronic lymphocytic leukemia (B-CLL) cells… 
Highly Cited
1984
Highly Cited
1984
Homocysteine in tissues of the mouse and rat.
Highly Cited
1977
Highly Cited
1977
Kinetics of inhibition of deoxynucleotide-polymerizing enzyme activities from normal and leukemic human cells by 9-beta-D-arabinofuranosyladenine 5'-triphosphate and 1-beta-D-arabinofuranosylcytosine…
Both 9-β-D-arabinofuranosyladenine 5′-triphosphate (aATP) and 1-β-D-arabinofuranosylcytosine 5′-triphosphate (aCTP) inhibit… 
Highly Cited
1977
Highly Cited
1977
Mass Spectroscopic Identification of Cytokinins: Glucosyl Zeatin and Glucosyl Ribosylzeatin from Vinca rosea Crown Gall.
Mass spectrographic and chemical studies of the permethyl and trimethylsilyl ethers of two new cytokinins isolated from Vinca… 
Highly Cited
1975
Highly Cited
1975
THE UTILIZATION OF NUCLEOTIDES BY ANIMAL CELLS *
We have extended our studies on the toxicity of several arabinosyl nucleotides to L cells. In contrast to a short-term toxic… 
Highly Cited
1968
Highly Cited
1968
In vivo antiviral properties of biologically active compounds. II. Studies with influenza and vaccinia viruses.
The in vivo anti-influenza virus and antivaccinia virus activity of 156 biologically active compounds was determined. One of two… 
Highly Cited
1967
Highly Cited
1967
Inhibition of mammalian DNA polymerase by the 5'-triphosphate of 9-beta-D-arabinofuranosyladenine.
The 5′-triphosphate of 9-β-d-arabinofuranosyladenine (ara-ATP) was tested as a substrate or inhibitor of polynucleotide synthesis… 
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