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Vidarabine

Known as: 9 beta D Arabinofuranosyladenine, Araadenosine, beta Ara A 
A nucleoside analog with activity against herpes simplex virus and varicella zoster virus. Vidarabine is converted to a monophosphate by viral… Expand
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (20)

6-dimethylaminopurine arabinoside6-methylaminopurine arabinoside9-alpha-arabinofuranosyl-8-azaadenine9-arabinofuranosyl-6-azidopurine
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Broader (3)

AntimetabolitesAntiviral Agentsadenine nucleoside
Decreased Protein Synthesis [PE]Drug AllergyIn BloodKeratitis, Herpetic
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold
ABSTRACT This is the first of two invited articles reviewing the development of nucleoside‐analogue antiviral drugs, written for… Expand
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Review
2018
Review
2018
The ProTide Prodrug Technology: From the Concept to the Clinic
The ProTide technology is a prodrug approach developed for the efficient intracellular delivery of nucleoside analogue… Expand
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Highly Cited
2005
Highly Cited
2005
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells.
Recent studies have described malignant stem cells as central to the initiation, growth, and potential relapse of acute and… Expand
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Highly Cited
2002
Highly Cited
2002
The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation
Nuclear localization of the transcriptional activator NF-κB (nuclear factor κB) is controlled in mammalian cells by three… Expand
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Highly Cited
1998
Highly Cited
1998
Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: a multicenter phase II study.
Rituximab, a chimeric monoclonal antibody that binds specifically to the CD20 antigen, induced objective responses in 50% of… Expand
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Highly Cited
1997
Highly Cited
1997
Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: harnessing graft-versus-leukemia without myeloablative therapy.
The immune-mediated graft-versus-leukemia effect is important to prevent relapse after allogeneic progenitor cell transplantation… Expand
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Highly Cited
1993
Highly Cited
1993
Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line.
Previous studies have shown that the bcl-2 gene encodes a mitochondrial protein that contributes to neoplastic cell expansion… Expand
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Highly Cited
1986
Highly Cited
1986
Vidarabine versus acyclovir therapy in herpes simplex encephalitis.
We randomly assigned 208 patients who underwent brain biopsy for presumptive herpes simplex encephalitis to receive either… Expand
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Highly Cited
1984
Highly Cited
1984
ACYCLOVIR VERSUS VIDARABINE IN HERPES SIMPLEX ENCEPHALITIS: Randomised Multicentre Study in Consecutive Swedish Patients
One hundred and twenty-seven patients with suspected herpes simplex encephalitis were entered in a randomised, controlled… Expand
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Highly Cited
1981
Highly Cited
1981
Herpes simplex encephalitis: vidarabine therapy and diagnostic problems.
To learn more about the treatment of herpes simplex encephalitis with vidarabine, we conducted an uncontrolled study of 132… Expand
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