Assessing the root of bilaterian animals with scalable phylogenomic methods
New sequence data and methods strongly uphold previous suggestions that Acoelomorpha is sister clade to all other bilaterian animals, find diminishing evidence for the placement of the enigmatic Xenoturbella within Deuterostomia, and place Cycliophora with Entoprocta and EctoproCTa.
Deep metazoan phylogeny: when different genes tell different stories.
Primmorphs generated from dissociated cells of the sponge Suberites domuncula: a model system for studies of cell proliferation and cell death
Cytotoxic metabolites from the fungal endophyte Alternaria sp. and their subsequent detection in its host plant Polygonum senegalense.
From the Egyptian medicinal plant Polygonum senegalense the fungal endophyte Alternaria sp. was isolated. Extracts of the fungus grown either in liquid culture or on solid rice media exhibited…
Innate Immune Defense of the Sponge Suberites domuncula against Bacteria Involves a MyD88-dependent Signaling Pathway
Data indicate that S. domuncula is provided with an innate immune system against Gram-negative bacteria; the ligand LPS (a pathogen-associated molecular pattern) is recognized by the pattern recognition receptor (LPS-interacting protein), which interacts with MyD88.
Establishment of a primary cell culture from a sponge: primmorphs from Suberites domuncula
- W. Müller
- 17 March 1999
It is proposed that the primmorph system described here is a powerful novel model system to study basic mechanisms of cell proliferation and cell death; it can also be used in aquaculture, for the production of bioactive compounds and as a bioindicator system.
Bioactive metabolites from the endophytic fungus Ampelomyces sp. isolated from the medicinal plant Urospermum picroides.
Formation of siliceous spicules in the marine demosponge Suberites domuncula
- W. Müller, Matthias Rothenberger, A. Boreiko, W. Tremel, A. Reiber, H. Schröder
- BiologyCell and Tissue Research
- 10 June 2005
Immunohistological analysis has shown that silicatein exists in the axial canal (axial filament) and on the surface of the spicules, suggesting that they grow by apposition, and it is demonstrated that the enzymic reaction of silicatesin is inhibited by anti-silicatein antibodies.
Expression of silicatein and collagen genes in the marine sponge Suberites domuncula is controlled by silicate and myotrophin.
- A. Krasko, B. Lorenz, R. Batel, H. Schröder, I. Müller, W. Müller
- BiologyEuropean Journal of Biochemistry
- 1 August 2000
It was found that after increasing the concentration of soluble silicate in the seawater medium from around 1 microM to approximately 60 microM, this gene is strongly upregulated and the expression of collagen is also upregulated in those primmorphs which were treated with recombinant myotrophin obtained from the same sponge.
Biofabrication of biosilica-glass by living organisms.
- H. Schröder, Xiaohong Wang, W. Tremel, H. Ushijima, W. Müller
- BiologyNatural product reports (Print)
- 22 May 2008
The present stage of knowledge on structure, biochemical composition, and mechanisms of biosilica formation is reported, focusing particularly on sponges because of the enormous (nano)biotechnological potential of the enzymes involved in this process.