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Floxuridine

Known as: 1beta-D-2'-Deoxyribofuranosyl-5-flurouracil, 5 fluorodeoxyuridine, 5-Fluorouracil Deoxyriboside 
A fluorinated pyrimidine monophosphate analogue of 5-fluoro-2'-deoxyuridine-5'-phosphate (FUDR-MP) with antineoplastic activity. As an antimetabolite… 
National Institutes of Health

Related topics

Related topics

33 relations

Narrower (10)

5'deoxy-4',5-difluorouridine5-fluoro-2'-deoxyuridine5-fluorodeoxyuridine-dipalmitateFF 707

Broader (7)

Antimetabolites, AntineoplasticAntineoplastic AgentsAntiviral AgentsDeoxyuridine
Colorectal NeoplasmsDrug AllergyFloxuridine 500 MG InjectionGene Expression Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
5-Aza-Deoxycytidine Induces Selective Degradation of DNA Methyltransferase 1 by a Proteasomal Pathway That Requires the KEN Box, Bromo-Adjacent Homology Domain, and Nuclear Localization Signal
ABSTRACT 5-Azacytidine- and 5-aza-deoxycytidine (5-aza-CdR)-mediated reactivation of tumor suppressor genes silenced by promoter… 
Review
2003
Review
2003
The mechanism of action of radiosensitization of conventional chemotherapeutic agents.
It is not an exaggeration to state that most of the advances in curing cancer in the last decade have come from successful… 
Highly Cited
1990
Highly Cited
1990
A prospective, randomized evaluation of the treatment of colorectal cancer metastatic to the liver.
Over a 4-year period (1982 to 1986), 91 patients with solitary or multiple metastases from colorectal cancer were stratified… 
Highly Cited
1989
Highly Cited
1989
A randomized trial of continuous intravenous versus hepatic intraarterial floxuridine in patients with colorectal cancer metastatic to the liver: the Northern California Oncology Group trial.
In 1983, the Northern California Oncology Group (NCOG) instituted a randomized trial of intravenous (IV) versus intraarterial (IA… 
Highly Cited
1987
Highly Cited
1987
A prospective randomized trial of regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases.
Sixty-four patients were entered into a randomized trial that evaluated intra-arterial (I.A.) versus intravenous (I.V.) 5… 
Highly Cited
1987
Highly Cited
1987
Deoxyribonucleoside triphosphate imbalance. 5-Fluorodeoxyuridine-induced DNA double strand breaks in mouse FM3A cells and the mechanism of cell death.
Highly Cited
1982
Highly Cited
1982
Mutation assay at the thymidine kinase locus in diploid human lymphoblasts.
Highly Cited
1976
Highly Cited
1976
Separation of functional Schwann cells and neurons from normal peripheral nerve tissue
Highly Cited
1971
Highly Cited
1971
Sensitivity of Dictyostelium discoideum to nucleic acid analogues.
Highly Cited
1970
Highly Cited
1970
INHIBITION OF MYOBLAST FUSION AFTER ONE ROUND OF DNA SYNTHESIS IN 5-BROMODEOXYURIDINE
The thymidine analogue 5-bromodeoxyuridine (BUdR) has a differential effect on the synthesis of tissue-specific products and… 
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