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Colorectal Neoplasms
Known as:
Tumor, Colorectal
, Large Intestine Neoplasm
, Tumor of the Large Bowel
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A benign or malignant neoplasm that affects the colon or rectum. Representative examples of benign neoplasms include lipoma and leiomyoma…
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National Institutes of Health
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Related topics
Related topics
48 relations
10 ML oxaliplatin 5 MG/ML Injection
Adenomatous Polyposis Coli
Aldesleukin
Anorectal Diseases
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Broader (2)
Colonic Diseases
Intestinal Neoplasms
Narrower (6)
Colonic Neoplasms
Colorectal Cancer
Colorectal Carcinoma
Rectal Neoplasms
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2014
K. Jung
,
Y. Won
,
C. Oh
,
H. Kong
,
D. Lee
,
K. Lee
Cancer research and treatment : official journal…
2017
Corpus ID: 1653322
Purpose This study presents the 2014 nationwide cancer statistics in Korea, including cancer incidence, survival, prevalence, and…
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Highly Cited
2005
Highly Cited
2005
Wnt signalling induces maturation of Paneth cells in intestinal crypts
J. V. Es
,
P. Jay
,
+9 authors
H. Clevers
Nature Cell Biology
2005
Corpus ID: 15151752
Wnt signalling, which is transduced through β-catenin/TCF4, maintains the undifferentiated state of intestinal crypt progenitor…
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Highly Cited
2005
Highly Cited
2005
Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.
H. Shigematsu
,
Takao Takahashi
,
+10 authors
A. Gazdar
Cancer Research
2005
Corpus ID: 18665347
Mutations in the epidermal growth factor receptor gene (EGFR) in lung cancers predict for sensitivity to EGFR kinase inhibitors…
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Highly Cited
2004
Highly Cited
2004
Computed tomographic colonography (virtual colonoscopy): a multicenter comparison with standard colonoscopy for detection of colorectal neoplasia.
P. Cotton
,
V. Durkalski
,
+18 authors
H. Butler
Journal of the American Medical Association (JAMA…
2004
Corpus ID: 3553240
CONTEXT Conventional colonoscopy is the best available method for detection of colorectal cancer; however, it is invasive and not…
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Review
2000
Review
2000
Progression model for pancreatic cancer.
R. Hruban
,
M. Goggins
,
Jennifer Parsons
,
S. Kern
Clinical Cancer Research
2000
Corpus ID: 10114212
It has been >10 years since Vogelstein and colleagues [(1][1] [, 2)][2] proposed a progression model for colorectal neoplasia in…
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Highly Cited
1998
Highly Cited
1998
Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis.
T. Chan
,
P. Morin
,
B. Vogelstein
,
K. Kinzler
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 21413321
Nonsteroidal antiinflammatory drugs (NSAIDs) can inhibit colorectal tumorigenesis and are among the few agents known to be useful…
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Highly Cited
1996
Highly Cited
1996
Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group.
L. Clark
,
G. Combs
,
+13 authors
Taylor
Journal of the American Medical Association (JAMA…
1996
Corpus ID: 27409632
OBJECTIVE To determine whether a nutritional supplement of selenium will decrease the incidence of cancer. DESIGN A multicenter…
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Highly Cited
1996
Highly Cited
1996
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers
S. Thiagalingam
,
C. Lengauer
,
+9 authors
B. Vogelstein
Nature Genetics
1996
Corpus ID: 6920871
Chromosome deletions are the most common genetic events observed in cancer1–4. These deletions are generally thought to reflect…
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Highly Cited
1993
Highly Cited
1993
Folate, methionine, and alcohol intake and risk of colorectal adenoma.
E. Giovannucci
,
M. Stampfer
,
+5 authors
W. Willett
Journal of the National Cancer Institute
1993
Corpus ID: 12368257
BACKGROUND Reduced methylation of DNA may contribute to loss of the normal controls on proto-oncogene expression. In humans…
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Highly Cited
1992
Highly Cited
1992
Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors.
D. Sidransky
,
T. Tokino
,
+4 authors
B. Vogelstein
Science
1992
Corpus ID: 12919088
Colorectal (CR) tumors are usually curable if detected before metastasis. Because genetic alterations are associated with the…
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