Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Colorectal Cancer

Known as: Colon/rectal cancer, Cancers, Colorectal, Cancer colo-rectal 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Cancer is the second leading cause of death in the world and one of the major public health problems. Despite the great advances… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • table 2
Is this relevant?
Review
2019
Review
2019
Following initial successes in melanoma treatment, immunotherapy has rapidly become established as a major treatment modality for… Expand
  • figure 1
  • figure 2
  • table 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
2012
Highly Cited
2012
A main limitation of therapies that selectively target kinase signalling pathways is the emergence of secondary drug resistance… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Human cancer is caused by the accumulation of mutations in oncogenes and tumor suppressor genes. To catalog the genetic changes… Expand
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The elucidation of the human genome sequence has made it possible to identify genetic alterations in cancers in unprecedented… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
BACKGROUND Current evidence suggests that high red meat intake is associated with increased colorectal cancer risk. High fish… Expand
  • table 2
  • table 4
  • figure 2
  • figure 1
  • figure 3
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate signaling pathways important for neoplasia, including cell… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Aberrant WNT pathway signaling is an early progression event in 90% of colorectal cancers. It occurs through mutations mainly of… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Aberrant methylation of promoter region CpG islands is associated with transcriptional inactivation of tumor-suppressor genes in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
It has long been considered that genetic instability is an integral component of human neoplasia1–3. In a small fraction of… Expand
Is this relevant?