Intestinal Neoplasms

Members of the miR-34 family are induced by the tumor suppressor p53 and are known to inhibit epithelial-to-mesenchymal… Expand

The cyclooxygenase (COX)-2 gene encodes an inducible prostaglandin synthase enzyme that is overexpressed in adenocarcinomas and… Expand

Small intestinal neoplasms are uncommonly encountered in clinical practice. They may occur sporadically, in association with… Expand

Matrilysin is a matrix metalloproteinase expressed in the tumor cells of greater than 80% of intestinal adenomas. The majority of… Expand

Recent epidemiologic studies have shown a 40-50% reduction in mortality from colorectal cancer in individuals who take… Expand

A considerable amount of evidence collected from several different experimental systems indicates that cyclooxygenase-2 (COX-2… Expand

Matrix metalloproteinases (MMPs) classically have been implicated in basement membrane destruction associated with late-stage… Expand

The term "gastrointestinal stromal tumor" (GIST) has been applied to mesenchymal tumors that represent neither typical leiomyomas… Expand

Germ-line mutations in the human adenomatous polyposis coli (APC) gene result in familial adenomatous polyposis, an autosomal… Expand

Introduction Histological Classification of Intestinal Tumours Small Intestine Appendix Large Intestine Anal Canal Anal Margin… Expand