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FZD7 protein, human

Known as: Frizzled Homolog 7, frizzled homolog 7 (Drosophila), human, FZE3 
Frizzled-7 (574 aa, ~64 kDa) is encoded by the human FZD7 gene. This protein is involved in Wnt-dependent G protein-coupled receptor signaling.
National Institutes of Health

Related topics

Related topics

16 relations
FZD7 geneFrizzled DomainG Protein-Coupled Receptor GenesG Protein-Coupled Receptor Signaling

Broader (1)

Frizzled Receptors

Papers overview

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Highly Cited
2011
Highly Cited
2011
FZD7 has a critical role in cell proliferation in triple negative breast cancer
Breast cancer is genetically and clinically heterogeneous. Triple negative breast cancer (TNBC) is a subtype of breast cancer… 
Highly Cited
2007
Highly Cited
2007
Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis
BackgroundOsteoporosis, a disease of decreased bone mineral density represents a significant and growing burden in the western… 
Highly Cited
2006
Highly Cited
2006
Identification and Functional Analysis of Candidate Genes Regulating Mesenchymal Stem Cell Self‐Renewal and Multipotency
Adult human mesenchymal stem cells (hMSCs) possess multilineage differentiation potential, and differentiated hMSCs have recently… 
Highly Cited
2006
Highly Cited
2006
Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity
Little is known about how protocadherins function in cell adhesion and tissue development. Paraxial protocadherin (PAPC) controls… 
Highly Cited
2005
Highly Cited
2005
Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma.
BACKGROUND/AIMS The molecular mechanisms of hepatocarcinogenesis remain largely unknown. Previous studies suggest that activation… 
Highly Cited
2002
Highly Cited
2002
The planar polarity gene strabismus regulates convergent extension movements in Xenopus
The signaling mechanisms that specify, guide and coordinate cell behavior during embryonic morphogenesis are poorly understood… 
Highly Cited
2001
Highly Cited
2001
Frizzled-7 signalling controls tissue separation during Xenopus gastrulation
Cell signalling through Frizzled receptors has evolved to considerable complexity within the metazoans. The Frizzled-dependent… 
Highly Cited
2000
Highly Cited
2000
Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis.
Wnt signalling plays a crucial role in the control of morphogenetic movements. We describe the expression and functional analyses… 
Highly Cited
2000
Highly Cited
2000
Xenopus frizzled 7 can act in canonical and non-canonical Wnt signaling pathways: implications on early patterning and morphogenesis
Highly Cited
2000
Highly Cited
2000
The putative wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorsoventral mesoderm patterning.
We have isolated one member of the frizzled family of wnt receptors from Xenopus (Xfz7) to study the role of cell-cell… 
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