Characterization of the apical papilla and its residing stem cells from human immature permanent teeth: a pilot study.
- W. Sonoyama, Yi Liu, G. T. Huang
- Biology, MedicineJournal of Endodontics
- 1 February 2008
Electrospun nanofibrous structure: a novel scaffold for tissue engineering.
- Wan-Ju Li, C. Laurencin, E. Caterson, R. Tuan, F. Ko
- Biology, Materials ScienceJournal of Biomedical Materials Research
- 15 June 2002
A novel poly(D,L-lactide-co-glycolide) (PLGA) structure with a unique architecture produced by an electrospinning process has been developed for tissue-engineering applications, which acts to support and guide cell growth.
Comparison of Proliferative and Multilineage Differentiation Potential of Human Mesenchymal Stem Cells Derived from Umbilical Cord and Bone Marrow
Gene array analysis showed that HUCPVCs also expressed Wnt signaling pathway genes that have been implicated in the regulation of MSCs, which support the applicability of HU CPVCs for cell‐based therapies.
Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy
A model for the regulation of MSC differentiation is proposed, and recent findings regarding theregulation of M SC differentiation are discussed.
Cellular interactions and signaling in cartilage development.
- A. DeLise, L. Fischer, R. Tuan
- BiologyOsteoarthritis and Cartilage
- 1 September 2000
In this review an extensive examination of historical and recent literature pertaining to limb development and mesenchymal condensation has been undertaken, with a focus on the development of cartilage.
Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation
- Catherine M. Kolf, Elizabeth Cho, R. Tuan
- BiologyArthritis Research & Therapy
- 19 February 2007
Recent advances in understanding the cellular and molecular signaling pathways and global transcriptional regulators of adult mesenchymal stem cells have provided new insights into their biology and…
Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells
- G. Boland, Geraldine Perkins, D. Hall, R. Tuan
- BiologyJournal of Cellular Biochemistry
- 15 December 2004
The results showed that sFRP3 treatment attenuates some of the observed Wnt 3a effects on MSCs, and that inhibition of canonical Wnt signaling using a dominant negative TCF1 enhances MSC osteogenesis.
A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells.
Concise Review: The Surface Markers and Identity of Human Mesenchymal Stem Cells
- F. Lv, R. Tuan, Kenneth C. P. Cheung, V. Leung
- BiologyStem Cells
- 1 June 2014
The reported expression of surface molecules in MSCs from various sources are revisited, aiming to assess their potential as MSC markers and define the critical panel for future investigation.
Stem/progenitor cell-mediated de novo regeneration of dental pulp with newly deposited continuous layer of dentin in an in vivo model.
- G. T. Huang, T. Yamaza, S. Shi
- Materials Science, BiologyTissue Engineering. Part A
- 1 February 2010
This study provides the first evidence showing that pulp- like tissue can be regenerated de novo in emptied root canal space by stem cells from apical papilla and dental pulp stem cells that give rise to odontoblast-like cells producing dentin-like tissue on existing dentinal walls.