Frizzled Receptors

Known as: Frizzled Proteins, Receptor, Frizzled, Receptors, Frizzled 
A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
0102019952017

Papers overview

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Highly Cited
2012
Highly Cited
2012
The Wnt/β-catenin pathway, which signals through the Frizzled (Fzd) receptor family and several coreceptors, has long been… (More)
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Highly Cited
2012
Highly Cited
2012
LGR5+ stem cells reside at crypt bottoms, intermingled with Paneth cells that provide Wnt, Notch and epidermal growth factor… (More)
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Highly Cited
2006
Highly Cited
2006
A set of conserved molecules guides axons along the metazoan dorsal-ventral axis. Recently, Wnt glycoproteins have been shown to… (More)
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Highly Cited
2005
Highly Cited
2005
Secreted frizzled related protein 1 (SFRP1) is an antagonist of the transmembrane frizzled receptor, a component of the Wnt… (More)
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Highly Cited
2004
Highly Cited
2004
Aberrant WNT pathway signaling is an early progression event in 90% of colorectal cancers. It occurs through mutations mainly of… (More)
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Highly Cited
2001
Highly Cited
2001
The frizzled receptors, which mediate development and display seven hydrophobic, membrane-spanning segments, are cell membrane… (More)
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Highly Cited
2000
Highly Cited
2000
Frizzled receptors are components of the Wnt signalling pathway, but how they activate the canonical Wnt/beta-catenin pathway is… (More)
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Highly Cited
1999
Highly Cited
1999
Frizzled related proteins (FRPs) comprise a family of secreted molecules that contain an N-terminal cysteine-rich domain (CRD… (More)
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Highly Cited
1999
Highly Cited
1999
Wingless (Wg) protein is a founding member of the Wnt family of secreted proteins which have profound organizing roles in animal… (More)
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Highly Cited
1997
Highly Cited
1997
This paper describes the identification of a new family of mammalian genes that encode secreted proteins containing homology to… (More)
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