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Frizzled Receptors

Known as: Frizzled Proteins, Receptor, Frizzled, Receptors, Frizzled 
A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY… 
National Institutes of Health

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FZD1 protein, humanFZD2 protein, humanFZD3 protein, humanFZD4 protein, human
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Frizzled Receptors as Potential Therapeutic Targets in Human Cancers
Frizzled receptors (FZDs) are a family of seven-span transmembrane receptors with hallmarks of G protein-coupled receptors (GPCRs… 
Highly Cited
2013
Highly Cited
2013
WNT1 mutations in families affected by moderately severe and progressive recessive osteogenesis imperfecta.
Highly Cited
2007
Highly Cited
2007
Wnt'er in liver: Expression of Wnt and frizzled genes in mouse
The Wnt signaling pathway is essential for a wide array of developmental and physiological processes. Wnts are extracellular… 
Highly Cited
2004
Highly Cited
2004
Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize β-catenin independently of Frizzled proteins
Secreted signaling proteins of the Wnt family are known to regulate a diverse range of developmental processes, and their… 
Highly Cited
2003
Highly Cited
2003
Frizzled receptor dimerization is sufficient to activate the Wnt/β-catenin pathway
Wnt signaling has an important role in cell-fate determination, tissue patterning and tumorigenesis. Wnt proteins signal through… 
Highly Cited
2002
Highly Cited
2002
Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas
The diverse receptor-ligand pairs of the Wnt and frizzled (Fz) families play important roles during embryonic development, and… 
Highly Cited
2001
Highly Cited
2001
Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis.
Wnts are secreted signaling molecules implicated in various developmental processes and frizzled proteins are the receptors for… 
Highly Cited
2000
Highly Cited
2000
Signaling specificity by Frizzled receptors in Drosophila.
Wnt-Frizzled (Fz) signaling pathways play recurring important roles during the development and homeostasis of vertebrates and… 
Highly Cited
1998
Highly Cited
1998
Frizzled-8 is expressed in the Spemann organizer and plays a role in early morphogenesis.
Wnts are secreted signaling molecules implicated in a large number of developmental processes. Frizzled proteins have been… 
Highly Cited
1997
Highly Cited
1997
A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.
This paper describes the identification of a new family of mammalian genes that encode secreted proteins containing homology to… 
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