FZD4 protein, human

Known as: CD344 Antigen, frizzled-4 protein, human, Frizzled 4 
Frizzled-4 (537 aa, ~60 kDa) is encoded by the human FZD4 gene. This protein is involved in Wnt binding and G protein-coupled receptor signaling.
National Institutes of Health

Papers overview

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2012
2012
The purpose of this study was to identify new tumor suppressor microRNAs (miRNA; miR) in bladder cancer, conduct functional… (More)
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Highly Cited
2010
Highly Cited
2010
TMPRSS2-ERG and other gene fusions involving ETS factors and genes with strong promoter elements are common in prostate cancer… (More)
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2009
Highly Cited
2009
Mutations in the genes encoding the Wnt receptor Frizzled-4 (FZD4), coreceptor LRP5, or the ligand Norrin disrupt retinal… (More)
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Highly Cited
2006
Highly Cited
2006
Wnts are lipid-modified secreted glycoproteins that regulate diverse biological processes. We report that Wnt5a, which functions… (More)
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2005
Highly Cited
2005
Previous studies showed that transcripts encoding specific Wnt ligands and Frizzled receptors including Wnt4, Frizzled1 (Fzd1… (More)
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2005
2005
Activating Flt3 mutations occur in about 30% of patients with acute myeloid leukemia (AML), often as in-frame internal tandem… (More)
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Highly Cited
2004
Highly Cited
2004
Familial exudative vitreoretinopathy (FEVR) is an inherited blinding disorder of the retinal vascular system. Autosomal dominant… (More)
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Highly Cited
2004
Highly Cited
2004
Incomplete retinal vascularization occurs in both Norrie disease and familial exudative vitreoretinopathy (FEVR). Norrin, the… (More)
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Highly Cited
2003
Highly Cited
2003
To detect novel Wnt-pathway genes involved in tumourigenesis, this study analysed the RNA expression levels of 40 genes of the… (More)
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2002
Highly Cited
2002
Familial exudative vitreoretinopathy (FEVR) is a hereditary ocular disorder characterized by a failure of peripheral retinal… (More)
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