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FZD1 protein, human

Known as: FzE1, Frizzled-1, hFz1 
Frizzled-1 (647 aa, ~71 kDa) is encoded by the human FZD1 gene. This protein is involved in the regulation of Wnt protein signaling.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The closure of an open anatomical structure by the directed growth and fusion of two tissue masses is a recurrent theme in… Expand
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Highly Cited
2009
Highly Cited
2009
The development of chemoresistance represents a major obstacle in the successful treatment of cancers such as neuroblastoma (NB… Expand
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Highly Cited
2005
Highly Cited
2005
The Wnt signaling pathway has recently been demonstrated to play an important role in bone cell function. In previous studies… Expand
Highly Cited
2004
Highly Cited
2004
The Wnt genes encode a family of related, secreted proteins which initiate a signal cascade upon binding to cell surface receptor… Expand
Highly Cited
2004
Highly Cited
2004
Corin is a type II transmembrane serine protease and functions as the proatrial natriuretic peptide (pro-ANP) convertase in the… Expand
Highly Cited
2004
Highly Cited
2004
Members of the low density lipoprotein receptor family (LDLR), LRP5/6, were shown to interact with the Frizzled (Fz) receptors… Expand
Highly Cited
2001
Highly Cited
2001
The frizzled receptors, which mediate development and display seven hydrophobic, membrane-spanning segments, are cell membrane… Expand
Highly Cited
1999
Highly Cited
1999
The human homologue of fz1 (Hfz1) was cloned from a cDNA library. Hfz1 was shown to couple to Wnt signal transduction pathways by… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Wnts are secreted proteins implicated in cell-cell interactions during embryogenesis and tumorigenesis, but receptors… Expand
Highly Cited
1992
Highly Cited
1992
The frizzled (fz) locus of Drosophila encodes a protein (Fz) with a seven-transmembrane-domain profile characteristic of G… Expand