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FFAR1 gene

Known as: G PROTEIN-COUPLED RECEPTOR 40, Free Fatty Acid Receptor 1 Gene, GPR40 
This gene plays a role in G protein signaling.
National Institutes of Health

Related topics

Related topics

7 relations
Energy MetabolismFree Fatty Acid Receptor 1G Protein-Coupled Receptor SignalingLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Synthesis, biological evaluation, and molecular docking investigation of benzhydrol- and indole-based dual PPAR-γ/FFAR1 agonists.
2016
2016
Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo Efficacy.
The free fatty acid receptor 1 (FFA1 or GPR40) is established as an interesting potential target for treatment of type 2 diabetes… 
2015
2015
Dose-response estrogen promotes osteogenic differentiation via GPR40 (FFAR1) in murine BMMSCs.
Review
2013
Review
2013
The therapeutic potential of GPR120: a patent review
Introduction: Type 2 diabetes (T2D) is a complex metabolic disorder characterized by persistent hyperglycemia and a wide range of… 
Highly Cited
2010
Highly Cited
2010
G-protein-coupled receptor 40 (GPR40) expression and its regulation in human pancreatic islets: the role of type 2 diabetes and fatty acids.
2009
2009
Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42.
GPR41 and GPR42 are two closely related genes that are part of a cluster of four adjacent G protein-coupled receptors (GPCRs… 
2008
2008
Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists.
2008
2008
Production and characterization of a monoclonal antibody against GPR40 (FFAR1; free fatty acid receptor 1).
2007
2007
Regulation of the Gene Encoding GPR40, a Fatty Acid Receptor Expressed Selectively in Pancreatic β Cells*
GPR40 is a G protein-coupled receptor expressed preferentially in pancreatic β cells. It is activated by long-chain fatty acids… 
Highly Cited
2005
Highly Cited
2005
Role of GPR40 in fatty acid action on the beta cell line INS-1E.
GPR40 is a G protein-coupled receptor expressed preferentially in beta cells, that has been implicated in mediating free fatty… 
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