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FFAR1 gene

Known as: G PROTEIN-COUPLED RECEPTOR 40, Free Fatty Acid Receptor 1 Gene, GPR40 
This gene plays a role in G protein signaling.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Objectives GPR40 (FFAR1), a clinically proven anti-diabetes target, is a Gq-coupled receptor for long chain fatty acids (LCFA… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Activation of free fatty acid receptor 1 (FFAR1; also known as G-protein-coupled receptor 40) by fatty acids… Expand
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Highly Cited
2012
Highly Cited
2012
G-protein-coupled receptor 40 (GPR40), highly expressed in pancreatic β-cells, mediates free fatty acid (FFA)-induced insulin… Expand
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE—The G-protein–coupled receptor Gpr40 is expressed in β-cells where it contributes to free fatty acid (FFA) enhancement… Expand
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE— Acute activation of G protein–coupled receptor 40 (GPR40) by free fatty acids (FFAs) or synthetic GPR40 agonists… Expand
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Highly Cited
2008
Highly Cited
2008
A series of 4-phenethynyldihydrocinnamic acid agonists of the free fatty acid receptor 1 (FFA(1)) has been discovered and… Expand
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Review
2008
Review
2008
The pancreatic beta-cell senses blood nutrient levels and is modulated by neurohormonal signals so that it secretes insulin… Expand
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Highly Cited
2008
Highly Cited
2008
The G-protein-coupled receptor free fatty acid receptor 1 (FFAR1), previously named GPR40, is a possible novel target for the… Expand
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Highly Cited
2005
Highly Cited
2005
Obesity is typically associated with elevated levels of free fatty acids (FFAs) and is linked to glucose intolerance and type 2… Expand
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Highly Cited
2003
Highly Cited
2003
GPR40 is a member of a subfamily of homologous G protein-coupled receptors that include GPR41 and GPR43 and that have no current… Expand
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