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Incompatibilities of Pharmaceutical Excipients with Active Pharmaceutical Ingredients: A Comprehensive Review
TLDR
The present review covers the literature reports of incompatibilities of commonly used pharmaceutical excipients with different active pharmaceutical ingredients.
Phloroglucinol compounds of natural origin.
TLDR
This review covers the phytochemistry and pharmacology of naturally occurring phloroglucinols, describing 700 compounds and containing a total of 484 references.
Anti-HIV natural products
TLDR
The spread of HIV in India has been di- verse, with much of India having a low rate of infection and the epidemic being most extreme in the southern states, with main focus on recent outcomes from natural sources as anti-HIV agents.
Cyclin-dependent kinase inhibition by flavoalkaloids.
TLDR
The present review comprises discovery, medicinal chemistry, pharmacology and preclinical/clinical development of flavoalkaloids as CDK inhibitors.
Non-enzymatic browning in citrus juice: chemical markers, their detection and ways to improve product quality
TLDR
2,5-Dimethyl-4-hydroxy-3(2H)-furanone (DMHF) is one of the promising marker formed during browning process with number of analytical methods reported for its analysis; therefore it can be used as an indicator for NEB process.
Natural alkaloids as P-gp inhibitors for multidrug resistance reversal in cancer.
Kinase inhibitors of marine origin.
Meridianins: marine-derived potent kinase inhibitors.
TLDR
The analysis of the structure-activity relationships of this family of compounds highlights the existence of various potential leads for the development of novel anticancer and anti-Alzheimer's agents.
Fascaplysin Induces Caspase Mediated Crosstalk Between Apoptosis and Autophagy Through the Inhibition of PI3K/AKT/mTOR Signaling Cascade in Human Leukemia HL‐60 Cells
TLDR
It was demonstrated that fascaplysin induced a cooperative interaction between apoptotic and autophagic pathways to induce cytotoxicity in HL‐60 cells, and detailed insight was provided by which both the pathways acted cooperatively to elicit fascaplyin induced cell death in HL-60 cells.
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