FCGR3A protein, human

Known as: Fc-Gamma RIII, FcgammaRIIIA, Fc-Gamma RIIIA 
Low affinity immunoglobulin gamma Fc region receptor III-A (254 aa, ~29 kDa) is encoded by the human FCGR3A gene. This protein is involved in… (More)

Topic mentions per year

Topic mentions per year

1989-2017
0102019892017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Distinct genes encode 6 human receptors for IgG (hFcgammaRs), 3 of which have 2 or 3 polymorphic variants. The specificity and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
2007
Highly Cited
2007
PURPOSE Cetuximab, a chimeric immunoglobulin G 1 (IgG1) anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The FCGR3A gene dimorphism generates two allotypes: FcgammaRIIIa-158V and FcgammaRIIIa-158F. The genotype homozygous for… (More)
  • table 1
  • figure 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
OBJECTIVE CD16 (IgG Fcgamma receptor type IIIA [FcgammaRIIIA])-expressing CD14+ monocytes express high levels of Toll-like… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Lec13 cells, a variant Chinese hamster ovary cell line, were used to produce human IgG1 that were deficient in fucose attached to… (More)
  • figure 1
  • table I
  • table II
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Given that the FcgammaRIIIa receptor 158V allotype displays a higher affinity for human immunoglobulin G1 and increased antibody… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Given that the Fc RIIIa receptor 158V allotype displays a higher affinity for human immunoglobulin G1 and increased antibody… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
1998
Highly Cited
1998
We report a novel method for measuring forward and reverse kinetic rate constants, kf0 and kr0, for the binding of individual… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
A novel polymorphism in the extracellular domain 2 (EC2) of FcgammaRIIIA affects ligand binding by natural killer (NK) cells and… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Tumor-associated lymphocytes (TALs) freshly isolated from patients with cancer usually manifest reduced proliferative and… (More)
  • table 1
  • table 2
  • figure 1
  • table 3
  • figure 2
Is this relevant?