Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

FCGR3A gene

Known as: Fc gamma receptor IIIa, CD16, Fc fragment of IgG receptor IIIa 
This gene plays a role in the mediation of antibody-dependent cytotoxicity and phagocytosis.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
To improve recruitment and activation of natural killer (NK) cells to lyse tumor cells, we isolated a human anti-CD16A antibody… Expand
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Tumor engraftment followed by monoclonal antibody (mAb) therapy targeting tumor antigens represents a gold standard for assessing… Expand
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Human Fcã receptors (FcãRs) are glycoproteins that bind the Fc region of IgG. The genes encoding the low‐affinity FcãRs are… Expand
Is this relevant?
Highly Cited
2007
Highly Cited
2007
PURPOSE Cetuximab, a chimeric immunoglobulin G 1 (IgG1) anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb… Expand
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The precise mechanism of rituximab plus cyclophosphamide/doxorubicin/vincristine/prednisone (R-CHOP) therapy in diffuse large B… Expand
  • table 1
  • table 3
  • figure 1
  • table 4
  • figure 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The FCGR3A gene dimorphism generates two allotypes: FcγRIIIa-158V and FcγRIIIa-158F. The genotype homozygous for FcγRIIIa-158V… Expand
  • table 1
  • figure 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Aim : To test the hypothesis of an association between polymorphism in FCGR3A (the gene coding for FcγRIIIa, which is expressed… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Given that the FcgammaRIIIa receptor 158V allotype displays a higher affinity for human immunoglobulin G1 and increased antibody… Expand
  • table 1
  • figure 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
OBJECTIVE Human low-affinity Fcgamma receptors (FcgammaR) constitute a clustered gene family located on chromosome 1q23, that… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Inflammatory cytokines and low‐affinity Fcγ receptor (FcγR) polymorphisms were investigated in 37 children with chronic immune… Expand
Is this relevant?