FCGR3A gene

Known as: Fc gamma receptor IIIa, CD16, Fc fragment of IgG receptor IIIa 
This gene plays a role in the mediation of antibody-dependent cytotoxicity and phagocytosis.
National Institutes of Health

Papers overview

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2010
2010
Polymorphisms of activating Fc-γ receptors (FCGRs) on natural killer cells and macrophages result in variable affinity for… (More)
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2010
2010
In order to investigate the influence of functional polymorphisms of macrophage migration inhibitory factor (MIF), Fcg receptors… (More)
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Highly Cited
2009
Highly Cited
2009
Human Fcgamma receptors (FcgammaRs) are glycoproteins that bind the Fc region of IgG. The genes encoding the low-affinity… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE Cetuximab, a chimeric immunoglobulin G 1 (IgG1) anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb… (More)
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Highly Cited
2006
Highly Cited
2006
The precise mechanism of rituximab plus cyclophosphamide/doxorubicin/vincristine/prednisone (R-CHOP) therapy in diffuse large B… (More)
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2006
2006
PURPOSE Anti-GD2 murine IgG3 antibody 3F8 kills neuroblastoma cells by antibody-dependent cell-mediated cytotoxicity (ADCC… (More)
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Highly Cited
2004
Highly Cited
2004
The FCGR3A gene dimorphism generates two allotypes: FcgammaRIIIa-158V and FcgammaRIIIa-158F. The genotype homozygous for… (More)
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Highly Cited
2004
Highly Cited
2004
AIM To test the hypothesis of an association between polymorphism in FCGR3A (the gene coding for FcgammaRIIIa, which is expressed… (More)
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Highly Cited
2002
Highly Cited
2002
Given that the FcgammaRIIIa receptor 158V allotype displays a higher affinity for human immunoglobulin G1 and increased antibody… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE Human low-affinity Fcgamma receptors (FcgammaR) constitute a clustered gene family located on chromosome 1q23, that… (More)
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