FCGR3A wt Allele

Known as: FCGRIII, Fc Fragment of IgG, Low Affinity IIIA, Receptor for (CD16A) Gene, CD16 
Human FCGR3A wild-type allele is located within 1q23 and is approximately 8 kb in length. This allele, which encodes low affinity immunoglobulin… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2018
024619892018

Papers overview

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2014
2014
To improve recruitment and activation of natural killer (NK) cells to lyse tumor cells, we isolated a human anti-CD16A antibody… (More)
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2012
2012
PURPOSE The goal of this research was to harness a monoclonal antibody (mAb) discovery platform to identify cell-surface antigens… (More)
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2010
2010
AIMS Given the importance of IgG Fc receptors in immune regulation, we hypothesized that Fcg receptor type III (FcgRIII, CD16… (More)
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Highly Cited
2007
Highly Cited
2007
Monoclonal antibodies (mAb) are widely used in the treatment of non-Hodgkin's lymphoma and autoimmune diseases. Although the… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Macrophages release cytokines, such as tumor necrosis factor alpha (TNF alpha), interleukin-1 (IL-1), and IL-6, which… (More)
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2001
2001
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector… (More)
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1995
1995
CD16, the low affinity Fc gamma receptor III for IgG (Fc gamma RIII), exists as a polypeptide-anchored form (Fc gamma RIIIA or… (More)
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1993
1993
New strategies are required to clinically exploit the ability of monoclonal antibodies to target tumor for lysis by cellular… (More)
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Highly Cited
1989
Highly Cited
1989
In the present study we have identified and characterized three subpopulations of peripheral blood NK cells based on the surface… (More)
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