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FCGR3A wt Allele

Known as: FCGRIII, Fc Fragment of IgG, Low Affinity IIIA, Receptor for (CD16A) Gene, CD16 
Human FCGR3A wild-type allele is located within 1q23 and is approximately 8 kb in length. This allele, which encodes low affinity immunoglobulin… Expand
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
Summary With the use of a mouse model expressing human Fc-gamma receptors (FcγRs), we demonstrated that antibodies with isotypes… Expand
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Highly Cited
2015
Highly Cited
2015
AFM13 is a bispecific, tetravalent chimeric antibody construct (TandAb) designed for the treatment of CD30-expressing… Expand
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Highly Cited
2009
Highly Cited
2009
Because macrophages have been implicated as major players in the mechanism of action of rituximab, we have investigated the… Expand
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Highly Cited
2007
Highly Cited
2007
HIV-1 persists in peripheral blood monocytes in individuals receiving highly active antiretroviral therapy (HAART) with viral… Expand
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Highly Cited
2007
Highly Cited
2007
Monoclonal antibodies (mAb) are widely used in the treatment of non-Hodgkin's lymphoma and autoimmune diseases. Although the… Expand
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Highly Cited
2001
Highly Cited
2001
The glycosylphosphatidylinositol-anchored receptor CD14 plays a major role in the inflammatory response of monocytes to… Expand
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Highly Cited
1998
Highly Cited
1998
We report a novel method for measuring forward and reverse kinetic rate constants, kf0 and kr0, for the binding of individual… Expand
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Highly Cited
1993
Highly Cited
1993
The CD14+/CD16+ cells account for about 10% of all blood monocytes. They are characterized by a low level expression of the CD14… Expand
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Highly Cited
1989
Highly Cited
1989
NATURAL killer cells are a population of T-cell–receptornegative (CD3–) lymphocytes that spontaneously mediate the lysis of… Expand
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Highly Cited
1988
Highly Cited
1988
Human phagocytic cells express receptors for the constant (Fc) region of immunoglobulin G. Neutrophils carry Fc receptor II… Expand
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