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FAS wt Allele

Known as: Tumor Necrosis Factor Receptor Superfamily, Member 6 Gene, APO-1, APT1 
Human FAS wild-type allele is located in the vicinity of 10q24.1 and is approximately 26 kb in length. This allele, which encodes tumor necrosis… 
National Institutes of Health

Related topics

Related topics

18 relations
10q24.1Alzheimer's Disease Pathway KEGGApoptosisBystander B Cell Activation Pathway

Broader (1)

FAS gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Prolonged intrathecal release of soluble Fas following severe traumatic brain injury in humans
Highly Cited
2000
Highly Cited
2000
Immune down‐regulation and peripheral deletion of CD8 T cells does not require TNF receptor‐ligand interactions nor CD95 (Fas, APO‐1)
TNF receptor‐ligand interactions and CD95 (Fas / APO‐1) have been demonstrated to be involved in activation‐induced death of… 
Highly Cited
1999
Highly Cited
1999
Fas ligand promotes cell survival of immature human bone marrow CD34+CD38- hematopoietic progenitor cells by suppressing apoptosis.
1999
1999
A high serum soluble Fas/APO-1 level is associated with a poor outcome of aggressive non-Hodgkin’s lymphoma
Soluble Fas (sFas) in the serum is believed to be able to inhibit apoptosis of lymphocytes. It has been reported that the serum… 
Review
1997
Review
1997
Portrait of an executioner: the molecular mechanism of FAS/APO-1-induced apoptosis.
Fas/APO-1 is a member of the TNF receptor family and plays a dominant role in the immune system, down-regulating the immune… 
Highly Cited
1997
Highly Cited
1997
Anti-Fas IgG1 antibodies recognizing the same epitope of Fas/APO-1 mediate different biological effects in vitro.
Fas/APO-1 is a cell surface glycoprotein that mediates programmed cell death or apoptosis when cross-linked with agonistic anti… 
Highly Cited
1995
Highly Cited
1995
Opposing roles of CD95 (Fas/APO-1) and CD40 in the death and rescue of human low density tonsillar B cells.
The regulation of B cell death plays roles in the selection of Ag-specific B cells in humoral immune responses, controlling B… 
Highly Cited
1995
Highly Cited
1995
Frequent expression of FAS/APO‐1 in Hodgkin's disease and anaplastic large cell lymphomas FAS/APO‐1 in Hodgkin's disease and anaplastic large cell lymphomas
FAS/APO‐1 (CD95) is a membrane glycoprotein belonging to the tumour necrosis factor/nerve growth factor receptor family, and… 
Highly Cited
1992
Highly Cited
1992
Expression of the APO-1 antigen in Burkitt lymphoma cell lines correlates with a shift towards a lymphoblastoid phenotype.
APO-1 is a cell surface molecule that induces apoptosis when ligated with the monoclonal antibody anti-APO-1. Expression of APO-1… 
1992
1992
Regulatory gene INO4 of yeast phospholipid biosynthesis is positively autoregulated and functions as a transactivator of fatty acid synthase genes FAS1 and FAS2 from Saccharomyces cerevisiae.
The sequence motif 5' TYTTCACATGY 3' functions as an upstream activation site common to both yeast fatty acid synthase genes… 
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