FAS gene

Known as: TNF receptor superfamily member 6, Fas Cell Surface Death Receptor Gene, APO-1 
This gene is involved in the mediation of cellular surface receptors and apoptotic signals.
National Institutes of Health

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Highly Cited
2000
Highly Cited
2000
BACKGROUND The death of cardiac cells during ischemia and reperfusion is partially mediated by apoptosis, as seen, eg, in autopsy… (More)
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Highly Cited
1998
Highly Cited
1998
Apoptotic cell suicide initiated by ligation of CD95 (Fas/APO-1) occurs through recruitment, oligomerization and autocatalytic… (More)
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Highly Cited
1998
Highly Cited
1998
Polyclonal horse antilymphocyte and rabbit antithymocyte globulins (ATGs) are currently used in severe aplastic anemia and for… (More)
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Highly Cited
1996
Highly Cited
1996
The Fas/APO-1-receptor associated cysteine protease Mch5 (MACH/FLICE) is believed to be the enzyme responsible for activating a… (More)
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Highly Cited
1996
Highly Cited
1996
Intracellular proteases appear to be important mediators of apoptosis. Substrates cleaved by proteases during apoptosis include… (More)
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Highly Cited
1995
Highly Cited
1995
THE APO-l/(Fas/CD95) cell surface receptor is a member of the nerve growth factor (NGF)/tumour necrosis factor (TNF) receptor… (More)
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Highly Cited
1995
Highly Cited
1995
Fas/APO-1 is a cell surface protein known to trigger apoptosis upon specific antibody engagement. Because wild-type p53 can… (More)
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Highly Cited
1995
Highly Cited
1995
The majority of human malignant glioma cells express Fas/APO-1 and are susceptible to Fas/APO-1 antibody-mediated apoptosis in… (More)
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Highly Cited
1994
Highly Cited
1994
Fas/APO-1 is a transmembrane protein of the nerve growth factor/TNF alpha receptor family which signals apoptotic cell death in… (More)
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Highly Cited
1994
Highly Cited
1994
Fas/APO-1 is a cell surface protein known to trigger apoptosis in a variety of cell types upon specific antibody binding… (More)
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