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10q24.1

A chromosome band present on 10q
National Institutes of Health

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5 relations
10qChromosomesFAS wt AlleleFRAT1 wt Allele
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Papers overview

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Highly Cited
2011
Highly Cited
2011
Genome-Wide Association Study for Atopy and Allergic Rhinitis in a Singapore Chinese Population
Allergic rhinitis (AR) is an atopic disease which affects about 600 million people worldwide and results from a complex interplay… Expand
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2009
2009
Nucleotide Excision Repair Pathway Polymorphisms and Pancreatic Cancer Risk: Evidence for role of MMS19L
Background: Nucleotide excision repair is a vital response to DNA damage, including damage from tobacco exposure. Single… Expand
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Highly Cited
2004
Highly Cited
2004
A novel locus for pure recessive hereditary spastic paraplegia maps to 10q22.1‐10q24.1
The hereditary spastic paraplegias (HSPs) are a group of clinically and genetically heterogeneous disorders characterized by… Expand
2001
2001
FRAT1 and FRAT2, clustered in human chromosome 10q24.1 region, are up-regulated in gastric cancer.
FRAT1 and FRAT2 are cancer-associated genes encoding GSK-3beta-binding proteins. Over-expression of FRAT1 or FRAT2 lead to… Expand
2001
2001
Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway.
FRAT1 positively regulates the WNT signaling pathway by stabilizing beta-catenin through the association with glycogen synthase… Expand
Highly Cited
1999
Highly Cited
1999
Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium.
The Wnt/frizzled cell signaling pathway has been implicated in the determination of polarity in a number of systems, including… Expand
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1994
1994
Fluorescence in situ hybridization analysis of chromosomal localization of three human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1
SummaryChromosomal localization of three human cytochrome P450 genes belonging to the CYP2C subfamily (CYP2C8, 2C9, and 2C10) was… Expand
Highly Cited
1993
Highly Cited
1993
In situ localization of the genetic locus encoding the lysosomal acid lipase/cholesteryl esterase (LIPA) deficient in Wolman disease to chromosome 10q23.2-q23.3.
Human acid lipase/cholesteryl esterase (EC 3.1.1.13) is a 46-kDa glycoprotein required for the lysosomal hydrolysis of… Expand
Highly Cited
1992
Highly Cited
1992
Assignment of the human Fas antigen gene (Fas) to 10q24.1.
 
Highly Cited
1988
Highly Cited
1988
Human cytochrome P-450 PB-1: a multigene family involved in mephenytoin and steroid oxidations that maps to chromosome 10.
The cytochrome P-450 monooxygenase system possesses catalytic activity toward many exogenous compounds (e.g., drugs, insecticides… Expand
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