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F 13640

Known as: F13640 
National Institutes of Health

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Related topics

3 relations

Broader (2)

PiperidinesPyridines

Narrower (1)

befiradol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Improvement of lower urinary tract function by a selective serotonin 5-HT1A receptor agonist, NLX-112, after chronic spinal cord injury
2018
2018
18F-F13640 preclinical evaluation in rodent, cat and primate as a 5-HT1A receptor agonist for PET neuroimaging
Serotonin 1A receptors are known to play an important role in many psychiatric and neurodegenerative disorders. Currently, all… 
2017
2017
Distinctive in vitro signal transduction profile of NLX‐112, a potent and efficacious serotonin 5‐HT1A receptor agonist
NLX‐112 (befiradol, F13640) is a selective serotonin 5‐HT1A receptor agonist. Although it has been tested in vivo, little has… 
2016
2016
The novel 5-HT1A receptor agonist, NLX-112 reduces l-DOPA-induced abnormal involuntary movements in rat: A chronic administration study with microdialysis measurements
Highly Cited
2015
Highly Cited
2015
NLX-112, a novel 5-HT1A receptor agonist for the treatment of l-DOPA-induced dyskinesia: Behavioral and neurochemical profile in rat
2015
2015
5-HT1A Receptor Agonist Befiradol Reduces Fentanyl-induced Respiratory Depression, Analgesia, and Sedation in Rats
Background:There is an unmet clinical need to develop a pharmacological therapy to counter opioid-induced respiratory depression… 
2010
2010
[3H]-F13640, a novel, selective and high-efficacy serotonin 5-HT1A receptor agonist radioligand
F13640 is a selective and high-efficacy serotonin 5-HT1A receptor agonist that demonstrates outstanding analgesic potential in… 
2009
2009
Region-specific changes in 5-HT1A agonist-induced Extracellular signal-Regulated Kinases 1/2 phosphorylation in rat brain: A quantitative ELISA study
2005
2005
The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain.
2002
2002
The 5-HT(1A) receptor agonist F 13640 attenuates mechanical allodynia in a rat model of trigeminal neuropathic pain.
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