Skip to search formSkip to main contentSkip to account menu
Opiate self-administration as a measure of chronic nociceptive pain in arthritic rats
View on Wolters Kluwer
Preclinical in vivo antitumor activity of vinflunine, a novel fluorinated Vinca alkaloid
TLDR
It is demonstrated that vinflunine is well tolerated and is definitively active against a range of experimental animal tumor models, with definite superiority over vinorelbine being shown in each tumor model evaluated.
View on Springer
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia
View on Elsevier
Profound, Non-Opioid Analgesia Produced by the High-Efficacy 5-HT1A Agonist F 13640 in the Formalin Model of Tonic Nociceptive Pain
TLDR
The results help to establish large-magnitude 5-HT1A receptor activation as a new molecular mechanism of profound, central analgesia and suggest that F 13640 may be particularly effective against pain arising from severe tonic nociceptive stimulation.
View on PubMed
F 11440, a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential.
TLDR
F 11440, shown here to be a potent, selective, high efficacy 5-HT1A receptor agonist, appears to have the potential to exert marked anxiolytic and antidepressant activity in humans.
View on PubMed
Pharmacological studies on zymosan inflammation in rats and mice. 1: Zymosan-induced paw oedema in rats and mice.
View on PubMed
F 11356, a novel 5-hydroxytryptamine (5-HT) derivative with potent, selective, and unique high intrinsic activity at 5-HT1B/1D receptors in models relevant to migraine.
TLDR
F 11356 is a selective, high-potency agonist at 5-HT1B/1D receptors, which distinguishes itself from tryptamine and derivatives in exerting high intrinsic activity at these receptors in vascular and neuronal models relevant to migraine.
View on PubMed
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats
View on Elsevier
Cutaneously applied erythromycin base reduces various types of inflammatory reactions in mouse ear.
TLDR
Results suggest some participation of an anti-inflammatory mechanism in the clinical effectiveness of cutaneously applied erythromycin base in some forms of acne.
View on PubMed
Pharmacological study of cantharidin-induced ear inflammation in mice.
View on PubMed
...
...
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License