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Ethylmorphine

Known as: (5Alpha,6Alpha)-7,8-Didehydro-4,5-Epoxy-3-Ethoxy-17-Methylmorphinan-6-Ol, Ethyl morphine, Ethylmorphine [Chemical/Ingredient] 
A narcotic analgesic and antitussive. It is metabolized in the liver by ETHYLMORPHINE-N-DEMETHYLASE and used as an indicator of liver function.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
An ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method for screening of drugs in whole blood has… Expand
Highly Cited
2000
Highly Cited
2000
The CYP3A4 enzyme contributes to the disposition of more than 60 therapeutically important drugs and displays marked person-to… Expand
Highly Cited
1985
Highly Cited
1985
Rats were injected sc with 0.5 mg Cd/kg, 6 days/week, for up to 26 weeks. Hepatic and renal function and tissue Cd and… Expand
Highly Cited
1985
Highly Cited
1985
We administered triacetyloleandomycin (TAO) to rats and found that this macrolide antibiotic is the most efficacious inducer of… Expand
Highly Cited
1982
Highly Cited
1982
Eight different forms of cytochrome P-450 (P-450) were purified to electrophoretic homogeneity by a common procedure from liver… Expand
Highly Cited
1981
Highly Cited
1981
Abstract The compartmentation of hydrogen peroxide catabolism was studied in isolated hepatocytes. Hydrogen peroxide generation… Expand
Highly Cited
1975
Highly Cited
1975
During the purification of rabbit liver microsomal cytochrome P-450 (P-450LM), evidence was obtained for the occurrence of at… Expand
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Highly Cited
1972
Highly Cited
1972
Abstract Kinetic parameters of five substrates of the mixed function oxidase system were determined to ensure that the mixed… Expand
Highly Cited
1969
Highly Cited
1969
Abstract Species differences in the metabolism of ethylmorphine parallel differences in NADPH cytochrome P-450 reductase more… Expand
Highly Cited
1966
Highly Cited
1966
SKF 525-A and ten congeners were incubated with hepatic microsomes, and all were found to be N-dealkylated. The kinetics of the… Expand