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Ethylmorphine

Known as: (5Alpha,6Alpha)-7,8-Didehydro-4,5-Epoxy-3-Ethoxy-17-Methylmorphinan-6-Ol, Ethyl morphine, Ethylmorphine [Chemical/Ingredient] 
A narcotic analgesic and antitussive. It is metabolized in the liver by ETHYLMORPHINE-N-DEMETHYLASE and used as an indicator of liver function.
National Institutes of Health

Related topics

Related topics

15 relations

Broader (3)

Analgesics, OpioidAntitussive AgentsNarcotics

Narrower (4)

DionineVeralginethylmorphine-6-glucuronidenorethylmorphine
ETHYLMORPHINE HCLIn Bloodagonistsanalogs & derivatives

Papers overview

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Highly Cited
1987
Highly Cited
1987
Purification of human liver cytochrome P-450 catalyzing testosterone 6 beta-hydroxylation.
Two forms of cytochrome P-450 (P-450 human-1 and P-450 human-2) have been purified from human liver microsomes to electrophoretic… 
Highly Cited
1986
Highly Cited
1986
Comparison of cytochrome P-450 content and activities in liver microsomes of seven animal species, including man.
The cytochrome P-450 content found in human livers obtained post mortem was between 0.21-0.42 nmol/mg protein. The kinetic… 
Highly Cited
1982
Highly Cited
1982
Effects of oestradiol-17 beta and hypophysectomy on hepatic mixed function oxidases in rainbow trout.
The effects of oestradiol-17 beta and/or hypophysectomy on the metabolism of benzo (a) pyrene (BP), paranitroanisole (PNA… 
Highly Cited
1976
Highly Cited
1976
The effect of quantity and quality of dietary protein on drug metabolism.
Dietary protein deficiency is known to modify the response to the pharmacotoxicological activities of drugs and foreign compounds… 
Highly Cited
1976
Highly Cited
1976
Activation of 3':5'-cyclic AMP-dependent protein kinase and induction of ornithine decarboxylase as early events in induction of mixed-function oxygenases.
The parenteral administration of a single dose of 3-methylcholanthrene to rats caused an increase in the liver of the… 
1976
1976
Biochemical changes after hepatic injury from toxic doses of acetaminophen or furosemide.
The effects of hepatotoxic doses of acetaminophen and furosemide on the function and composition of hepatic endoplasmic reticulum… 
1974
1974
Differences in distribution pattern of marker enzymes among subcellular fractions from Morris hepatoma 16.
Summary The distribution of marker enzymes in subcellular fractions isolated by differential centrifugation was determined in… 
Highly Cited
1973
Highly Cited
1973
Relationship between plasma antipyrine half-lives and hepatic microsomal drug metabolism in dogs.
Plasma antipyrine half-lives exhibited an inverse relationship to hepatic microsomal aniline hydroxylase (r = –0.78) and… 
Highly Cited
1972
Highly Cited
1972
Effect of protein deprivation of male weanling rats on the kinetics of hepatic microsomal enzyme activity.
The effect of protein deficiency in male weanling rats on the activity of the hepatic microsomal enzyme system was studied… 
1971
1971
The microsomal fraction from Tetrahymena pyriformis strain ST: characterization and subfractionation.
Summary: Post-mitochondrial supernatants isolated from Tetrahymena pyriformis contained high specific activities of antimycin A… 
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