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Antitussive Agents

Known as: Cough Medicines, Antitussive Drugs, coughing suppressants 
Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (25)

ButorphanolCodeineDextromethorphanEthylmorphine

Broader (2)

Central Nervous System AgentsPharmaceutical Preparations
CoughingExpectorantsIn BloodNarcotic Antitussive [EPC]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: a double-blind randomized controlled trial.
Review
2013
Review
2013
Cancer drug discovery by repurposing: teaching new tricks to old dogs.
Review
2004
Review
2004
IDENTIFICATION AND CHARACTERIZATION OF POTENT CYP3A4 INHIBITORS IN SCHISANDRA FRUIT EXTRACT
Schisandra fruit, a Schisandraceae family herb, is used as a component in Kampo medicines (developed from Chinese medicines, but… 
Highly Cited
2004
Highly Cited
2004
Effect of Dextromethorphan, Diphenhydramine, and Placebo on Nocturnal Cough and Sleep Quality for Coughing Children and Their Parents
To the Editor. Paul et al1 did not prove that dextromethorphan and diphenhydramine are no better than placebo, because there was… 
Review
2002
Review
2002
Functional organization of the central cough generation mechanism.
Recent studies evaluating the effects of pulmonary afferents, chemoreceptors, and antitussive drugs on the cough motor pattern… 
Highly Cited
1996
Highly Cited
1996
Oral administration of dextromethorphan prevents the development of morphine tolerance and dependence in rats
Highly Cited
1993
Highly Cited
1993
Voluntary suppression of cough induced by inhalation of capsaicin in healthy volunteers.
Review
1989
Review
1989
Dextromethorphan and neuromodulation: old drug coughs up new activities.
Highly Cited
1989
Highly Cited
1989
Dextromethorphan protects retina against ischemic injury in vivo.
Retinal ischemia was induced in rabbits by increasing intraocular pressure above systolic blood pressure for 60 or 75 minutes… 
Highly Cited
1983
Highly Cited
1983
High-affinity dextromethorphan binding sites in guinea pig brain. II. Competition experiments.
Binding of dextromethorphan (DM) to guinea pig brain is stereoselective, since levomethorphan is 20 times weaker than DM in… 
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