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Dextromethorphan

Known as: Dextrometorfano, Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-, Dextromethorphanum 
A synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan… 
National Institutes of Health

Related topics

Related topics

41 relations
12 HR Dextromethorphan Hydrobromide 60 MG / Guaifenesin 1200 MG Extended Release Oral TabletAcetaminophen 325 MG / Dextromethorphan Hydrobromide 10 MG Oral Capsule [DayQuil HBP]Benzocaine 7.5 MG / Dextromethorphan Hydrobromide 5 MG Oral LozengeBenzocaine 7.5 MG / Dextromethorphan Hydrobromide 5 MG Oral Lozenge [Cepacol Sore Throat Plus Cough]

Narrower (10)

12 HR dextromethorphan polistirex 6 MG/ML Extended Release Suspension3-methoxymorphinanBenylinCardec DM

Broader (2)

Excitatory Amino Acid AntagonistsRacemethorphan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
DEXTROMETHORPHAN IS EFFECTIVE IN THE TREATMENT OF SUBACUTE METHOTREXATE NEUROTOXICITY
Methotrexate-induced neurotoxicity (MTX-Ntox) is a frequent complication of methotrexate (MTX) therapy for patients with both… 
Review
2000
Review
2000
Update on the neurophysiology of pain transmission and modulation: focus on the NMDA-receptor.
Highly Cited
1999
Highly Cited
1999
Anticough and antimicrobial activities of Psidium guajava Linn. leaf extract.
Highly Cited
1997
Highly Cited
1997
The d- and l- isomers of methadone bind to the non-competitive site on the N-methyl-d-aspartate (NMDA) receptor in rat forebrain and spinal cord
Highly Cited
1997
Highly Cited
1997
High‐dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia
N-methyl-D-aspartate (NMDA) receptor antagonists relieve neuropathic pain in animal models, but side effects of dissociative… 
Highly Cited
1995
Highly Cited
1995
Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo
Highly Cited
1994
Highly Cited
1994
The N-methyl-d-aspartate receptor antagonist dextromethorphan selectively reduces temporal summation of second pain in man
Highly Cited
1994
Highly Cited
1994
Glutamate antagonists have different effects on spontaneous locomotor activity in rats
Highly Cited
1993
Highly Cited
1993
Patch clamp studies on the kinetics and selectivity of N-methyl-d-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan)
Highly Cited
1988
Highly Cited
1988
Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI).
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