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3-methoxymorphinan

Known as: LK-3 compound, morphinan, 3-methoxy- 
 
National Institutes of Health

Papers overview

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2008
2008
BACKGROUND AND OBJECTIVES The aims of this study were to establish the potencies of epinephrine, bupivacaine, dextromethorphan, 3… Expand
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2007
2007
Dextromethorphan, an antitussive, has a complex pharmacologic profile and has not been well studied. Our aim was to evaluate… Expand
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2002
2002
The objective of this study was to determine the effects of grapefruit juice and seville orange juice on dextromethorphan (DM… Expand
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Highly Cited
2001
Highly Cited
2001
Dextromethorphan (DXM) is a widely used probe drug for human CYP2D6 activity both in vitro and in vivo. In humans, DXM is… Expand
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Highly Cited
2000
Highly Cited
2000
PURPOSE The aims of these experiments were to determine the effect of a therapeutic regimen of dexamethasone on cytochrome… Expand
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1998
1998
Cytochromes mediating the biotransformation of dextromethorphan to dextrorphan and 3-methoxymorphinan, its principal metabolites… Expand
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Highly Cited
1997
Highly Cited
1997
The human clearance of omeprazole and lansoprazole is conducted primarily by the hepatic cytochrome P450 (CYP) system. Efficacy… Expand
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Highly Cited
1996
Highly Cited
1996
OBJECTIVES We studied the disposition of dextromethorphan in extensive and poor metabolizer subjects, as well as the effect of… Expand
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Highly Cited
1994
Highly Cited
1994
In an effort to identify the human cytochromes P450 involved in the N-demethylation of dextromethorphan, the kinetics of 3… Expand
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Highly Cited
1993
Highly Cited
1993
The metabolism of dextromethorphan, a drug used to probe genetically determined CYP2D6 activity has been investigated in vivo and… Expand
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