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3-methoxymorphinan

Known as: LK-3 compound, morphinan, 3-methoxy- 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

3-methoxymorphinan hydrochloride3-methoxymorphinan, (14alpha)-isomer

Broader (1)

Dextromethorphan
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
A validated SIM GC/MS method for the simultaneous determination of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in biological matrices and its…
Dextromethorphan is used as a probe drug for assessing CYP2D6 and CYP3A4 activity in vivo and in vitro. A SIM GC/MS method… 
2007
2007
Isobolographic Analysis of Epinephrine With Bupivacaine, Dextromethorphan, 3-Methoxymorphinan, or Dextrorphan on Infiltrative Anesthesia in Rats: Dose-Response Studies
Background and Objectives: The aims of this study were to establish the potencies of epinephrine, bupivacaine, dextromethorphan… 
2003
2003
New morphinan derivatives with negligible psychotropic effects attenuate convulsions induced by maximal electroshock in mice.
2002
2002
A sensitive LC-MS/MS assay for the determination of dextromethorphan and metabolites in human urine--application for drug interaction studies assessing potential CYP3A and CYP2D6 inhibition.
2002
2002
Effect of interferon α‐ribavirin bitherapy on cytochrome P450 1A2 and 2D6 and N‐acetyltransferase‐2 activities in patients with chronic active hepatitis C
Interferon α (IFN‐α) is thought to be responsible for cytochrome P450 (CYP)‐dependent drug interactions mediated by a decrease in… 
1999
1999
A Urine Metabolic Ratio of Dextromethorphan and 3‐Methoxymorphinan as a Probe for CYP3A Activity and Prediction of Cyclosporine Clearance in Healthy Volunteers
Dextromethorphan (DM) is metabolized in the body to dextrophan (DT) and 3‐methoxymorphinan (3‐MM) by cytochrome P450 (CYP) 2D6… 
Highly Cited
1996
Highly Cited
1996
Dextromethorphan as an in vivo probe for the simultaneous determination of CYP2D6 and CYP3A activity.
Highly Cited
1996
Highly Cited
1996
Quantification of dextromethorphan and metabolites: a dual phenotypic marker for cytochrome P450 3A4/5 and 2D6 activity.
1994
1994
Screening for hydroxylation and acetylation polymorphisms in man via simultaneous analysis of urinary metabolites of mephenytoin, dextromethorphan and caffeine by capillary electrophoretic procedures…
1993
1993
Primary and secondary oxidative metabolism of dextromethorphan. In vitro studies with female Sprague-Dawley and Dark Agouti rat liver microsomes.
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