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Codeine
Known as:
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-
, morphine 3-methyl ether
, N Methylmorphine
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A naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activities. Codeine mimics the actions…
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National Institutes of Health
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Related topics
Related topics
43 relations
Narrower (21)
ACC 30
Brompton mixture
Codeine / Guaifenesin
Codeine / Promethazine
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AMMONIUM CHLORIDE/CHLORPHENIRAMINE/CODEINE/PHENYLEPHRINE/POTASSI
Acetaminophen 300 MG / Codeine Phosphate 30 MG Oral Tablet
Aspirin 325 MG / butalbital 50 MG / Caffeine 40 MG / Codeine Phosphate 30 MG Oral Capsule [Ascomp]
Codeine Phosphate 2 MG/ML / Guaifenesin 20 MG/ML Oral Solution
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Broader (4)
Alkaloids
Analgesics
Narcotic Analgesics
Opiates
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update
K. Crews
,
A. Gaedigk
,
+10 authors
T. Skaar
Clinical pharmacology and therapeutics
2014
Corpus ID: 37092838
Codeine is bioactivated to morphine, a strong opioid agonist, by the hepatic cytochrome P450 2D6 (CYP2D6); hence, the efficacy…
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Review
2013
Review
2013
EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents.
R. Loos
,
R. Carvalho
,
+15 authors
B. Gawlik
Water research
2013
Corpus ID: 23163505
Review
2011
Review
2011
Emerging pollutants in wastewater: a review of the literature.
T. Deblonde
,
C. Cossu-Leguille
,
P. Hartemann
International journal of hygiene and…
2011
Corpus ID: 9724190
Highly Cited
2008
Highly Cited
2008
The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK.
B. Kasprzyk-Hordern
,
R. Dinsdale
,
A. Guwy
Water research
2008
Corpus ID: 6179878
Highly Cited
2007
Highly Cited
2007
Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication
J. Kirchheiner
,
H. Schmidt
,
+4 authors
J. Brockmöller
The Pharmacogenomics Journal
2007
Corpus ID: 6662662
Codeine is an analgesic drug acting on μ-opiate receptors predominantly via its metabolite morphine, which is formed almost…
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Highly Cited
2004
Highly Cited
2004
Codeine intoxication associated with ultrarapid CYP2D6 metabolism.
Y. Gasche
,
Y. Daali
,
+4 authors
J. Desmeules
The New England journal of medicine
2004
Corpus ID: 2059323
Life-threatening opioid intoxication developed in a patient after he was given small doses of codeine for the treatment of a…
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Review
2002
Review
2002
Laccase: new functions for an old enzyme.
A. Mayer
,
R. Staples
Phytochemistry
2002
Corpus ID: 43184051
Highly Cited
1987
Highly Cited
1987
The formalin test in mice: dissociation between inflammatory and non-inflammatory pain
S. Hunskaar
,
K. Hole
Pain
1987
Corpus ID: 31511006
Highly Cited
1975
Highly Cited
1975
The analgesic properties of delta‐9‐tetrahydrocannabinol and codeine
R. Noyes
,
S. Brunk
,
D. Avery
,
A. Canter
Clinical pharmacology and therapeutics
1975
Corpus ID: 7532991
The administration of single oral doses of delta‐9‐tetrahydrocannabinol (THC) to patients with cancer pain demonstrated a mild…
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Highly Cited
1972
Highly Cited
1972
Blood-Brain Barrier: Penetration of Morphine, Codeine, Heroin, and Methadone after Carotid Injection
W. Oldendorf
,
S. Hyman
,
L. Braun
,
S. Z. Oldendorf
Science
1972
Corpus ID: 11655498
Labeled morphine, codeine, heroin, or methadone was injected as a bolus into the common carotid artery of the rat, and the rat…
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