Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Codeine

Known as: Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-, morphine 3-methyl ether, N Methylmorphine 
A naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activities. Codeine mimics the actions… Expand
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (21)

ACC 30Brompton mixtureCodeine / GuaifenesinCodeine / Promethazine
Expand
AMMONIUM CHLORIDE/CHLORPHENIRAMINE/CODEINE/PHENYLEPHRINE/POTASSIAcetaminophen 300 MG / Codeine Phosphate 30 MG Oral TabletAspirin 325 MG / butalbital 50 MG / Caffeine 40 MG / Codeine Phosphate 30 MG Oral Capsule [Ascomp]Codeine Phosphate 2 MG/ML / Guaifenesin 20 MG/ML Oral Solution
Expand

Broader (4)

AlkaloidsAnalgesicsNarcotic AnalgesicsOpiates

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Clinical Practice Guideline: Tonsillectomy in Children (Update)
Objective This update of a 2011 guideline developed by the American Academy of Otolaryngology–Head and Neck Surgery Foundation… Expand
  • table 1
  • table 2
  • table 3
  • table 4
  • table 4
Review
2018
Review
2018
Interventions for Postsurgical Opioid Prescribing: A Systematic Review
Importance Over the past 20 years, opioid misuse and opioid addiction have risen to epidemic proportions in the United States… Expand
Review
2018
Review
2018
Representations of Codeine Misuse on Instagram: Content Analysis
Background Prescription opioid misuse has doubled over the past 10 years and is now a public health epidemic. Analysis of social… Expand
Review
2014
Review
2014
Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update
Codeine is bioactivated to morphine, a strong opioid agonist, by the hepatic cytochrome P450 2D6 (CYP2D6); hence, the efficacy… Expand
Highly Cited
2007
Highly Cited
2007
Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication
Codeine is an analgesic drug acting on μ-opiate receptors predominantly via its metabolite morphine, which is formed almost… Expand
  • table 1
  • table 2
  • figure 2
  • figure 1
  • table 3
Highly Cited
2006
Highly Cited
2006
Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother
In April, 2005, a full-term healthy male infant, delivered vaginally, showed intermittent periods of diffi culty in breastfeeding… Expand
Highly Cited
2004
Highly Cited
2004
Codeine intoxication associated with ultrarapid CYP2D6 metabolism.
Life-threatening opioid intoxication developed in a patient after he was given small doses of codeine for the treatment of a… Expand
Highly Cited
1987
Highly Cited
1987
The formalin test in mice: dissociation between inflammatory and non-inflammatory pain
&NA; The formalin test in mice is a valid and reliable model of nociception and is sensitive for various classes of analgesic… Expand
Highly Cited
1975
Highly Cited
1975
The analgesic properties of delta‐9‐tetrahydrocannabinol and codeine
The administration of single oral doses of delta‐9‐tetrahydrocannabinol (THC) to patients with cancer pain demonstrated a mild… Expand
Highly Cited
1972
Highly Cited
1972
Blood-Brain Barrier: Penetration of Morphine, Codeine, Heroin, and Methadone after Carotid Injection
Labeled morphine, codeine, heroin, or methadone was injected as a bolus into the common carotid artery of the rat, and the rat… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE