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Codeine

Known as: Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-, morphine 3-methyl ether, N Methylmorphine 
A naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activities. Codeine mimics the actions… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (21)

ACC 30Brompton mixtureCodeine / GuaifenesinCodeine / Promethazine
AMMONIUM CHLORIDE/CHLORPHENIRAMINE/CODEINE/PHENYLEPHRINE/POTASSIAcetaminophen 300 MG / Codeine Phosphate 30 MG Oral TabletAspirin 325 MG / butalbital 50 MG / Caffeine 40 MG / Codeine Phosphate 30 MG Oral Capsule [Ascomp]Codeine Phosphate 2 MG/ML / Guaifenesin 20 MG/ML Oral Solution

Broader (4)

AlkaloidsAnalgesicsNarcotic AnalgesicsOpiates

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
"Take ten minutes": a dedicated ten minute medication review reduces polypharmacy in the elderly.
Multiple and inappropriate medications are often the cause for poor health status in the elderly. Medication reviews can improve… 
2001
2001
Oral Ibuprofen Versus Paracetamol Plus Codeine for Analgesia After Ambulatory Surgery
he combination of oral codeine and acetamino-phen is often used for postdischarge pain controlafter ambulatory surgery. However… 
1996
1996
Urine and plasma pharmacokinetics of codeine in healthy volunteers: implications for drugs-of-abuse testing.
Thirteen healthy volunteers participating in an open and randomized study received two single doses (25 and 50 mg) of codeine… 
Highly Cited
1985
Highly Cited
1985
Detection of O6-monoacetylmorphine in urine samples by GC/MS as evidence for heroin use.
A method for qualitative and quantitative detection of nanogram amounts of O6-monoacetylmorphine (MAM) in urine samples of heroin… 
1982
1982
3H-Codeine binding in the guinea pig lower brain stem.
Saturable binding of (-)-3H codeine was found in the guinea pig medulla (KD = 5.6 x 10(-7) M, Bmax = 1.4 pmol/mg protein… 
1980
1980
Neonatal codeine withdrawal in infants of nonaddicted mothers.
The problem of neonatal narcotic withdrawal has been well described.1-4 The extensive literature on this topic has predominantly… 
Highly Cited
1977
Highly Cited
1977
A rapid, high-yield conversion of codeine to morphine.
Brief treatment of codeine (1) in chloroform with boron tribromide has consiste-tly given morphine (2) in 90-91% yield after a… 
1976
1976
A practical synthesis of codeine from dihydrothebainone.
The conversion of dihydrothebainone to codeine or thebaine has been achieved in high yield. Bromination and dehydrobromination… 
1966
1966
Gas chromatographic determination of codeine in serum and urine.
A method for gas chromatographic detection of codeine in serum is described. An application to a clinical drug evaluation study… 
1934
1934
THE ADDICTION LIABILITY OF CODEINE
Discussions have arisen from time to time concerning the addiction liability of codeine and its value as a therapeutic agent for… 
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