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Codeine
Known as:
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-
, morphine 3-methyl ether
, N Methylmorphine
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A naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activities. Codeine mimics the actions…
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National Institutes of Health
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Related topics
Related topics
43 relations
Narrower (21)
ACC 30
Brompton mixture
Codeine / Guaifenesin
Codeine / Promethazine
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AMMONIUM CHLORIDE/CHLORPHENIRAMINE/CODEINE/PHENYLEPHRINE/POTASSI
Acetaminophen 300 MG / Codeine Phosphate 30 MG Oral Tablet
Aspirin 325 MG / butalbital 50 MG / Caffeine 40 MG / Codeine Phosphate 30 MG Oral Capsule [Ascomp]
Codeine Phosphate 2 MG/ML / Guaifenesin 20 MG/ML Oral Solution
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Broader (4)
Alkaloids
Analgesics
Narcotic Analgesics
Opiates
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Application of poly(methacrylic acid‐ethylene glycol dimethacrylate) monolith microextraction coupled with capillary zone electrophoresis to the determination of opiates in human urine
F. Wei
,
M. Zhang
,
Yu-Qi Feng
Electrophoresis
2006
Corpus ID: 3170261
A novel poly(methacrylic acid‐ethylene glycol dimethacrylate) (MAA‐EGDMA) monolith microextraction method coupled with CZE was…
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2004
2004
Trouble with tramadol
K. Kaye
2004
Corpus ID: 77870946
During the preparation of the editorial there was a suggestion that the popularity of tramadol may be related to the...
1996
1996
Urine and plasma pharmacokinetics of codeine in healthy volunteers: implications for drugs-of-abuse testing.
Pierre Lafolie
,
Olof Beck
,
Zhen Lin
,
F. Albertioni
,
Lars O. Boreus
Journal of Analytical Toxicology
1996
Corpus ID: 5612960
Thirteen healthy volunteers participating in an open and randomized study received two single doses (25 and 50 mg) of codeine…
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Highly Cited
1985
Highly Cited
1985
Detection of O6-monoacetylmorphine in urine samples by GC/MS as evidence for heroin use.
J. Fehn
,
G. Megges
Journal of Analytical Toxicology
1985
Corpus ID: 46694980
A method for qualitative and quantitative detection of nanogram amounts of O6-monoacetylmorphine (MAM) in urine samples of heroin…
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1982
1982
Simultaneous quantitation of morphine and codeine in biological samples by electron impact mass fragmentography.
Nancy B. Wu Chen
,
M. Schaffer
,
Reng-Lang Lin
,
Robert J. Stein
Journal of Analytical Toxicology
1982
Corpus ID: 9527514
A method was developed for the quantitative determination of free morphine and codeine utilizing multiple ion detection mass…
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1982
1982
Effect of a low-fat diet and antidiarrhoeal agents on bowel habits after excisional surgery for classical Crohn's disease.
H. Andersson
,
Ingvar Bosaeus
,
R. Hellberg
,
Leif Hultén
Acta chirurgica Scandinavica
1982
Corpus ID: 20775851
The effect of dietary restriction and/or antidiarrhoeal agents on the bowel habits in relation to amount of ileal resection was…
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1981
1981
Efficient synthesis of 14-hydroxymorphinans from codeine.
M. Schwartz
,
R. Wallace
Journal of Medicinal Chemistry
1981
Corpus ID: 26785451
Codeine is converted to 7,8-dihydro-14-hydroxynorcodeinone (noroxycodone) in six steps and 52% overall yield of the…
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1977
1977
An improved method for O-demethylation of codeine.
J. Lawson
,
J. Degraw
Journal of Medicinal Chemistry
1977
Corpus ID: 20499918
The O-demethylation of codeine was effected by sodium propylmercaptide in dimethylformamide at 125 degrees C to afford morphine…
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1976
1976
A practical synthesis of codeine from dihydrothebainone.
D. Weller
,
H. Rapoport
Journal of Medicinal Chemistry
1976
Corpus ID: 46046210
The conversion of dihydrothebainone to codeine or thebaine has been achieved in high yield. Bromination and dehydrobromination…
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1966
1966
Gas chromatographic determination of codeine in serum and urine.
Emanuel Schmerzler
,
William Yu
,
M. Hewitt
,
I. Greenblatt
Journal of Pharmacy and Science
1966
Corpus ID: 35536036
A method for gas chromatographic detection of codeine in serum is described. An application to a clinical drug evaluation study…
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