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Codeine

Known as: Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-, morphine 3-methyl ether, N Methylmorphine 
A naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activities. Codeine mimics the actions… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (21)

ACC 30Brompton mixtureCodeine / GuaifenesinCodeine / Promethazine
AMMONIUM CHLORIDE/CHLORPHENIRAMINE/CODEINE/PHENYLEPHRINE/POTASSIAcetaminophen 300 MG / Codeine Phosphate 30 MG Oral TabletAspirin 325 MG / butalbital 50 MG / Caffeine 40 MG / Codeine Phosphate 30 MG Oral Capsule [Ascomp]Codeine Phosphate 2 MG/ML / Guaifenesin 20 MG/ML Oral Solution

Broader (4)

AlkaloidsAnalgesicsNarcotic AnalgesicsOpiates

Papers overview

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Highly Cited
2006
Highly Cited
2006
Application of poly(methacrylic acid‐ethylene glycol dimethacrylate) monolith microextraction coupled with capillary zone electrophoresis to the determination of opiates in human urine
A novel poly(methacrylic acid‐ethylene glycol dimethacrylate) (MAA‐EGDMA) monolith microextraction method coupled with CZE was… 
2004
2004
Trouble with tramadol
During the preparation of the editorial there was a suggestion that the popularity of tramadol may be related to the... 
1996
1996
Urine and plasma pharmacokinetics of codeine in healthy volunteers: implications for drugs-of-abuse testing.
Thirteen healthy volunteers participating in an open and randomized study received two single doses (25 and 50 mg) of codeine… 
Highly Cited
1985
Highly Cited
1985
Detection of O6-monoacetylmorphine in urine samples by GC/MS as evidence for heroin use.
A method for qualitative and quantitative detection of nanogram amounts of O6-monoacetylmorphine (MAM) in urine samples of heroin… 
1982
1982
3H-Codeine binding in the guinea pig lower brain stem.
Saturable binding of (-)-3H codeine was found in the guinea pig medulla (KD = 5.6 x 10(-7) M, Bmax = 1.4 pmol/mg protein… 
1982
1982
Simultaneous quantitation of morphine and codeine in biological samples by electron impact mass fragmentography.
A method was developed for the quantitative determination of free morphine and codeine utilizing multiple ion detection mass… 
1981
1981
Efficient synthesis of 14-hydroxymorphinans from codeine.
Codeine is converted to 7,8-dihydro-14-hydroxynorcodeinone (noroxycodone) in six steps and 52% overall yield of the… 
1976
1976
A practical synthesis of codeine from dihydrothebainone.
The conversion of dihydrothebainone to codeine or thebaine has been achieved in high yield. Bromination and dehydrobromination… 
1966
1966
Gas chromatographic determination of codeine in serum and urine.
A method for gas chromatographic detection of codeine in serum is described. An application to a clinical drug evaluation study… 
1934
1934
THE ADDICTION LIABILITY OF CODEINE
Discussions have arisen from time to time concerning the addiction liability of codeine and its value as a therapeutic agent for…