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Codeine

Known as: Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-, morphine 3-methyl ether, N Methylmorphine 
A naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activities. Codeine mimics the actions… Expand
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Codeine is bioactivated to morphine, a strong opioid agonist, by the hepatic cytochrome P450 2D6 (CYP2D6); hence, the efficacy… Expand
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Highly Cited
2012
Highly Cited
2012
In 2009 we reported the fatal case of a toddler who had received codeine after adenotonsillectomy for obstructive sleep apnea… Expand
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Highly Cited
2012
Highly Cited
2012
Codeine is bioactivated to morphine, a strong opioid agonist, by the hepatic cytochrome P450 2D6 (CYP2D6); hence, the efficacy… Expand
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Is this relevant?
Highly Cited
2009
Highly Cited
2009
A large number of women receive codeine for obstetric pain while breastfeeding. Following a case of fatal opioid poisoning in a… Expand
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Highly Cited
2007
Highly Cited
2007
Codeine is an analgesic drug acting on μ-opiate receptors predominantly via its metabolite morphine, which is formed almost… Expand
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Highly Cited
2006
Highly Cited
2006
In April, 2005, a full-term healthy male infant, delivered vaginally, showed intermittent periods of diffi culty in breastfeeding… Expand
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Highly Cited
2006
Highly Cited
2006
Background: Chronic noncancer pain (CNCP) is a major health problem, for which opioids provide one treatment option. However… Expand
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Highly Cited
2004
Highly Cited
2004
Life-threatening opioid intoxication developed in a patient after he was given small doses of codeine for the treatment of a… Expand
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Highly Cited
1987
Highly Cited
1987
The formalin test in mice is a valid and reliable model of nociception and is sensitive for various classes of analgesic drugs… Expand
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Highly Cited
1975
Highly Cited
1975
The administration of single oral doses of delta-9-tetrahydrocannabinol (THC) to patients with cancer pain demonstrated a mild… Expand
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