Safety assessment of allylalkoxybenzene derivatives used as flavouring substances - methyl eugenol and estragole.
Pharmacokinetics of acrylamide in Fisher-344 rats.
Dermal absorption of phthalate diesters in rats.
Ovotoxicity in female Fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: comparison through calculation of an ovotoxic index.
- S. M. Borman, P. Christian, I. Sipes, P. Hoyer
- Biology, MedicineToxicology and Applied Pharmacology
- 15 September 2000
It is predicted that DMBA is the most potent ovarian toxicant (lower OI) in both species but VCD damages primordial follicles after shorter exposures, while all three PAHs were more ovotoxic with repeated low-dose exposure compared with OIs calculated from other studies using single high-dose exposures.
Assessment of follicle destruction in chemical-induced ovarian toxicity.
This article focuses on chemicals that have been shown to destroy small follicles in laboratory animals and an ovotoxic compound of particular interest is 4-vinylcyclohexene (VCH) and its epoxide metabolites.
Metabolism of bisphenol a in primary cultured hepatocytes from mice, rats, and humans.
The extent of monoglucuronide formation in monolayers of hepatocytes from rats, mice, and humans was determined and when extrapolated to the whole liver, the hepatic capacity for BPA glucuronidation is predicted to be humans > rats > mice.
A toxicologic and dermatologic assessment of cinnamyl alcohol, cinnamaldehyde and cinnamic acid when used as fragrance ingredients.
A toxicological and dermatological assessment of aryl alkyl alcohols when used as fragrance ingredients.
Destruction of preantral follicles in adult rats by 4-vinyl-1-cyclohexene diepoxide.