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Ethotoin

Known as: ethotoin [Chemical/Ingredient], Etotoina, 1-Ethyl-2,5-dioxo-4-phenylimidazolidine 
A hydantoin anticonvulsant with anti-epileptic activity. The mechanism of action is not completely known, but is thought to be fairly similar to… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (3)

AnticonvulsantsHydantoin derivative anticonvulsantHydantoins
Antiepileptic AgentsDrug AllergyEpilepsyEthylphenylhydantoin

Narrower (1)

Peganone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Synthesis of novel biologically active heterocyclic compounds from 2-oxo-2H-benzopyran-6-yl-imidazolidine.
6-Aminocoumarin on treatment with oxalyl chloride gives coumarinyl-6-isocynate (1a-c) which on treatment with glycine gives 1H-3… 
2005
2005
Dissociation of I domain and global conformational changes in LFA-1: refinement of small molecule-I domain structure-activity relationships.
LFA-1 (alphalbeta2) is constitutively expressed on leukocytes, but its activity is rapidly regulated. This rapid activation has… 
1991
1991
Comparison of the behavioral teratogenic potential of phenytoin, mephenytoin, ethotoin, and hydantoin in rats.
Pregnant Sprague-Dawley CD rats were orally administered either phenytoin (PHT, 200 mg/kg), mephenytoin (MPH, 100 mg/kg… 
1983
1983
Nonlinear ethotoin kinetics
Five healthy subjects were given single 500‐, 1500‐, and 2500‐mg doses of ethotoin as 250‐mg tablets at 7‐day intervals. Plasma… 
1982
1982
Teratogenicity and lethality of hydantoin derivatives in the mouse: structure--toxicity relationships.
1981
1981
Binding of (3H)-5,5 diphenylhydantoin to rat brain membranes
1978
1978
Solid dispersions of nitrofurantoin, ethotoin, and coumarin with polyethylene glycol 6000 and their coprecipitates with providone 25,000.
The influence of two linear polymers, polyethylene glycol 6000 and povidone 25,000, on the dissolution rate of three poorly… 
1978
1978
Simultaneous liquid-chromatographic determination of 12 common sedatives and hypnotics in serum.
We present a method for simultaneously determining 12 hypnotics and sedatives (primidone, methyprylon, phenobarbital… 
1976
1976
SATURABLE METABOLIC PATHWAYS FOR ETHOTOIN IN MAN
1. The urinary excretion pattern of ethotoin and five metabolites were examined in three patients receiving continuous treatment… 
1973
1973
A radioimmunoassay for diphenylhydantoin.
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