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Ethotoin
Known as:
ethotoin [Chemical/Ingredient]
, Etotoina
, 1-Ethyl-2,5-dioxo-4-phenylimidazolidine
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A hydantoin anticonvulsant with anti-epileptic activity. The mechanism of action is not completely known, but is thought to be fairly similar to…
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National Institutes of Health
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Related topics
Related topics
13 relations
Broader (3)
Anticonvulsants
Hydantoin derivative anticonvulsant
Hydantoins
Antiepileptic Agents
Drug Allergy
Epilepsy
Ethylphenylhydantoin
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Narrower (1)
Peganone
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Synthesis of novel biologically active heterocyclic compounds from 2-oxo-2H-benzopyran-6-yl-imidazolidine.
V. Mulwad
,
B. Langi
,
A. Chaskar
Acta Poloniae Pharmaceutica - Drug Research
2011
Corpus ID: 30159729
6-Aminocoumarin on treatment with oxalyl chloride gives coumarinyl-6-isocynate (1a-c) which on treatment with glycine gives 1H-3…
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1991
1991
Comparison of the behavioral teratogenic potential of phenytoin, mephenytoin, ethotoin, and hydantoin in rats.
D. Minck
,
K. D. Acuff-Smith
,
C. Vorhees
Teratology
1991
Corpus ID: 44951803
Pregnant Sprague-Dawley CD rats were orally administered either phenytoin (PHT, 200 mg/kg), mephenytoin (MPH, 100 mg/kg…
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Review
1990
Review
1990
Adjunctive Therapy for Intractable Epilepsy with Ethotoin
V. Biton
,
J. Gates
,
F. Ritter
,
R. Loewenson
Epilepsia
1990
Corpus ID: 22891998
Summary: In a retrospective study, records of 46 patients (24 women and 22 men aged 17–51 years; mean 29.2 years), who had been…
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1984
1984
Ethotoin in seizures of childhood and adolescence
C. Carter
,
R. Helms
,
R. Boehm
Neurology
1984
Corpus ID: 33420415
Ethotoin is an anticonvulsant that was considered minimally effective when introduced, but due to its apparent lack of side…
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1983
1983
Nonlinear ethotoin kinetics
M. Meyer
,
B. Holcombe
,
Gilbert J. Burckart
,
G. Raghow
,
Martin Yau
Clinical pharmacology and therapy
1983
Corpus ID: 38008521
Five healthy subjects were given single 500‐, 1500‐, and 2500‐mg doses of ethotoin as 250‐mg tablets at 7‐day intervals. Plasma…
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1982
1982
Teratogenicity and lethality of hydantoin derivatives in the mouse: structure--toxicity relationships.
N. Brown
,
G. Shull
,
J. Kao
,
E. Goulding
,
S. Fabro
Toxicology and Applied Pharmacology
1982
Corpus ID: 19314939
1981
1981
Binding of (3H)-5,5 diphenylhydantoin to rat brain membranes
D. S. Shah
,
P. Chambon
,
A. Guidotti
Neuropharmacology
1981
Corpus ID: 44868733
1978
1978
Simultaneous liquid-chromatographic determination of 12 common sedatives and hypnotics in serum.
P. Kabra
,
H. Y. Koo
,
L. Marton
Clinical Chemistry
1978
Corpus ID: 37961686
We present a method for simultaneously determining 12 hypnotics and sedatives (primidone, methyprylon, phenobarbital…
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1976
1976
SATURABLE METABOLIC PATHWAYS FOR ETHOTOIN IN MAN
J. Næstoft
,
E. Hvidberg
,
O. Sjö
Clinical and Experimental Pharmacology and…
1976
Corpus ID: 8669716
1. The urinary excretion pattern of ethotoin and five metabolites were examined in three patients receiving continuous treatment…
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1973
1973
A radioimmunoassay for diphenylhydantoin.
R. Tigelaar
,
R. Rapport
,
J. Inman
,
H. Kupferberg
Clinica chimica acta; international journal of…
1973
Corpus ID: 2713286
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