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Hydantoin derivative anticonvulsant

Known as: Hydantoin 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
G-quadruplex is a four-stranded G-rich DNA structure that is highly susceptible to oxidation. Despite the important roles that G… 
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2015
2015
DNA topoisomerase I is a potential chemotherapeutic target. Here, we designed and synthesized a library comprising of hydantoin… 
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Highly Cited
2012
Highly Cited
2012
Accumulation of oxidative DNA damage has been proposed as a potential cause of age-related cognitive decline. The major pathway… 
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Highly Cited
2010
Highly Cited
2010
Human DNA glycosylase NEIL1 exhibits a superior ability to remove oxidized guanine lesions guanidinohydantoin (Gh) and… 
2001
2001
Abstract. Cloning and sequencing of a 7.1 kb DNA fragment from Agrobacterium sp IP I-671 revealed seven open reading frames (ORFs… 
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2001
2001
A series of hydantoin derivatives has been discovered as highly potent nonpeptide antagonists for the human CCR5 receptor. The… 
2000
2000
In Arthrobacter aurescens DSM 3747 three enzymes are involved in the complete conversion of slowly racemizing 5'-monosubstituted… 
1992
1992
DNA fragments containing the genes involved in the conversion of 5-substituted hydantoins to their corresponding L-amino acids… 
Review
1970
Review
1970
LYMPHADENOPATHY has been recognized as one of the less common side effects of the hydantoin drugs 1-3 for more than a quarter of… 
Highly Cited
1959
Highly Cited
1959
Trigeminal neuralgia (tic douloureux) is characterized by brief paroxysms of pain limited to the facial distribution of the…