Dantrolene

Known as: Dantrolenum, Dantrolene [Chemical/Ingredient], Dantroleno 
A hydantoin derivative and direct-acting skeletal muscle relaxant. Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding… (More)
National Institutes of Health

Papers overview

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Review
2016
Review
2016
A rapidly increasing number of papers describing novel iPSC models for cardiac diseases are being published. To be able to… (More)
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Highly Cited
2012
Highly Cited
2012
Coordinated release of calcium (Ca(2+) ) from the sarcoplasmic reticulum (SR) through cardiac ryanodine receptor (RYR2) channels… (More)
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2012
2012
Disruption of intracellular calcium homeostasis via abnormal and excessive activation of ryanodine receptors plays an important… (More)
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Highly Cited
2008
Highly Cited
2008
Drug-induced liver injury (DILI) is the most common adverse event causing drug nonapprovals and drug withdrawals. Using drugs as… (More)
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Highly Cited
2005
Highly Cited
2005
Interdomain interactions between N-terminal and central domains serving as a "domain switch" are believed to be essential to the… (More)
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Highly Cited
2002
Highly Cited
2002
Brain-derived neurotrophic factor (BDNF) plays a critical role in activity-dependent modifications of neuronal connectivity and… (More)
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Highly Cited
2001
Highly Cited
2001
As an inhibitor of Ca(2+) release through ryanodine receptor (RYR) channels, the skeletal muscle relaxant dantrolene has proven… (More)
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Highly Cited
1997
Highly Cited
1997
The skeletal muscle relaxant dantrolene inhibits the release of Ca2+ from the sarcoplasmic reticulum during excitation… (More)
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1996
1996
The neuroprotective effects of dantrolene, an inhibitor of calcium release from intracellular stores, were investigated in a… (More)
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Highly Cited
1979
Highly Cited
1979
1. The velocity of shortening at zero load was studied during fused tetanic contractions and single twitches in isolated skeletal… (More)
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