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Dantrolene

Known as: Dantrolenum, Dantrolene [Chemical/Ingredient], Dantroleno 
A hydantoin derivative and direct-acting skeletal muscle relaxant. Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding… 
National Institutes of Health

Related topics

Related topics

33 relations

Narrower (9)

5-hydroxydantroleneDantamacrinDantriumDantrolene Sodium
Calcium Channel Antagonists [MoA]Cerebral InfarctionCerebral PalsyDantrolene Sodium 100 MG Oral Capsule [Dantrium]

Broader (3)

Hydantoin derivative anticonvulsantMuscle Relaxants, CentralMuscle relaxants

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Mobilisation of intracellular Ca2+ by mGluR5 metabotropic glutamate receptor activation in neonatal rat cultured dorsal root ganglia neurones
Highly Cited
1997
Highly Cited
1997
Efficacy of Intraoperative Cooling Methods
Background: Patients may require perioperative cooling for a variety of reasons including treatment of a malignant hyperthermia… 
Highly Cited
1995
Highly Cited
1995
Dantrolene treatment for abrupt intrathecal baclofen withdrawal.
I ntrathecal administration of baclofen produces cerebrospinal fluid (CSF) concentrations 100 times greater than those occurring… 
Highly Cited
1992
Highly Cited
1992
Blockade of NMDA receptor-mediated mobilization of intracellular Ca2+ prevents neurotoxicity
Highly Cited
1992
Highly Cited
1992
Endothelin-1-stimulated glucose production in vitro in the isolated perfused rat liver.
Highly Cited
1990
Highly Cited
1990
Short and long term regulation of catecholamine biosynthetic enzymes by angiotensin in cultured adrenal medullary cells. Molecular mechanisms and nature of second messenger systems.
Highly Cited
1989
Highly Cited
1989
Regulation of muscle AChR α subunit gene expression by electrical activity: Involvement of protein kinase C and Ca 2+
Highly Cited
1989
Highly Cited
1989
Inositol trisphosphate induces calcium release from Neurospora crassa vacuoles.
Highly Cited
1988
Highly Cited
1988
Effects of caffeine and tetracaine on outer hair cell shortening suggest intracellular calcium involvement
Highly Cited
1986
Highly Cited
1986
Direct demonstration of adrenocorticotropin-induced changes in cytoplasmic free calcium with aequorin in adrenal glomerulosa cell.
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