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5-hydroxydantrolene

National Institutes of Health

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Dantrolene
analogs & derivatives

Papers overview

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2011
2011
Pharmacokinetics and metabolism of dantrolene in horses.
Dantrolene is a skeletal muscle relaxant used commonly in performance horses to prevent exertional rhabdomyolysis. The goal of… 
1990
1990
Pharmacokinetics of intravenously administered dantrolene and its 5-hydroxy metabolite in dogs.
Dantrolene, a direct acting muscle relaxant used orally for spasticity, has appeared to be effective in the prevention and… 
1986
1986
Relationship between serum concentration and daily dose of dantrolene in cerebral palsy patients.
Serum concentration of dantrolene and its active metabolite, 5-hydroxydantrolene were determined in 27 cerebral palsy patients… 
1982
1982
Simultaneous determination of dantrolene and its metabolites, 5-hydroxydantrolene and nitro-reduced acetylated dantrolene (F 490), in plasma and urine of man and dog by high-performance liquid…
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