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Ethylphenylhydantoin

Known as: nirvanol, (+-)-3-Ethyl-5-phenylhydantoin, 5-phenyl-5-ethylhydantoin 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

AnticonvulsantsHydantoin derivative anticonvulsantMephenytoin
EthotoinPeganoneanalogs & derivatives

Papers overview

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2004
2004
Quantification of mephenytoin and its metabolites 4'-hydroxymephenytoin and nirvanol in human urine using a simple sample processing method.
A reliable and easy to use liquid chromatography/tandem mass spectrometry (LC/MS/MS) method without the use of sample extraction… 
1997
1997
TGF-alpha sustains clonal expansion by promoter-dependent, chemically initiated rat hepatocytes.
A series of promoting and non-promoting barbiturates and hydantoins were examined for their ability to sustain the growth of a… 
1993
1993
Pharmacodynamics of cytochrome P450 2B induction by phenobarbital, 5-ethyl-5-phenylhydantoin, and 5-ethyl-5-phenyloxazolidinedione in the male rat liver or in cultured rat hepatocytes.
The pharmacodynamics of rat hepatic cytochrome P450 2B (P450 2B) induction by phenobarbital (PB) and two structural congeners, dl… 
Highly Cited
1984
Highly Cited
1984
Mephenytoin and sparteine pharmacogenetics in Canadian Caucasians
The frequency of genetically deficient hydroxylation of mephenytoin (M‐defect) was studied in 83 healthy Caucasians living in… 
1982
1982
Analysis of hydroxylated and demethylated metabolites of mephenytoin in man and laboratory animals using gas-liquid chromatography and high-performance liquid chromatography.
1977
1977
Gas Chromatographic On‐Column Methylation Technique for the Simultaneous Determination of Antiepileptic Drugs in Blood
An on‐column methylation technique (OCMT) is described for th e simultaneous, gas chromatographic determination in blood of… 
1975
1975
Anticonvulsants. 5. Derivatives of 5-ethyl-5-phenylhydantoin and 5,5-diphenylhydantoin.
Alkoxymethyl, acyloxymethyl, and mixed alkylalkoxymethyl or alkylacyloxymethyl derivatives of 5-ethyl-5-phenylhydantoin exhibit… 
1969
1969
Thin-layer chromatography of anticonvulsant drugs.
A rapid semiquantitative method for the determination of anticonvulsant drugs in blood and urine by thin-layer chromatography is… 
1940
1940
Severe Toxic Effects of Sodium Diphenyl Hydantoinate in Mentally Defective Epileptics
Sodium diphenylhydantoinate exhibited in the treatment of 20 male epileptic oligophrenics resulted in many toxic manifestations… 
1932
1932
THE TREATMENT OF OBSTINATE CHOREA WITH NIRVANOL: WITH NOTES ON ITS MODE OF ACTION
During the last fifteen years the capacity of nirvanol to produce a syndrome known as "nirvanol sickness" has been widely… 
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