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Ethylphenylhydantoin

Known as: nirvanol, (+-)-3-Ethyl-5-phenylhydantoin, 5-phenyl-5-ethylhydantoin 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Background:Metabolism and clearance of racemic methadone are stereoselective and highly variable, yet the mechanism remains… 
Highly Cited
2004
Highly Cited
2004
SummaryInherited deficiency in mephenytoin hydroxylation was observed in a family study. It is important that the propositus was… 
Highly Cited
2002
Highly Cited
2002
Highly potent and selective CYP2C19 inhibitors are not currently available. In the present study, N-3-benzyl derivatives of… 
Highly Cited
2002
Highly Cited
2002
Cytochrome P450 2B6 is a genetically polymorphic enzyme that is important in the metabolism of a number of clinically used drugs… 
Highly Cited
2000
Highly Cited
2000
The in vitro biotransformation of bupropion to hydroxybupropion was studied in human liver microsomes and microsomes containing… 
Highly Cited
1998
Highly Cited
1998
Previous studies in this laboratory have determined the lack of specificity of several antibody and substrate probes of CYP2B6… 
Review
1997
Highly Cited
1997
Highly Cited
1997
7-Ethoxy-4-trifluoromethylcoumarin (7-EFC) was examined as a substrate for cytochrome P450 (P450) in microsomes from human livers… 
Highly Cited
1996
Highly Cited
1996
In vitro methods were used to identify the cytochrome P450 (CYP) enzyme(s) involved in S-mephenytoin N-demethylation. S…