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Etanidazole

Known as: 1H-Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-, 2-Nitroimidazole-1-acetamide, N-(2-hydroxyethyl)-, Etanidazole [Chemical/Ingredient] 
A 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the… 
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (3)

2-nitroimidazole EF5SR-2508fluoroetanidazole

Broader (3)

Antineoplastic AgentsNitroimidazolesRadiation-Sensitizing Agents
Glutathione S-TransferaseIn Bloodagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Subcutaneous study on the controlled release of Etanidazole and Taxol for the treatment of Glioma
BALB/c nude mice 6 weeks old were inoculated with glioma C6 cell-line and the efficacy of the different amount of Etanidazole… 
2004
2004
Delivery of Etanidazole to Brain Tumor from PLGA Wafers
This paper presents the computer simulation results on the delivery of Etanidazole (radiosensitiser) to the brain tumor and… 
2001
2001
Validation of the RTOG recursive partitioning classification for head and neck tumors
We previously demonstrated that a mathematical technique called recursive partitioning analysis (RPA), when applied to the… 
2000
2000
Sensitization of Radiation-induced Apoptosis of HL-60 Cells by Etanidazole
1996
1996
Mechanisms and implications of the low dose intrinsic radiation survival response
Previous studies in this laboratory using a precise assay for measurement of cell survival revealed substructure in the radiation… 
1992
1992
Session C: Concepts and Developments in Cell Sensitization FIRST ANALYSIS ON TUMOR REGRESSION FOR THE EUROPEAN RANDOMIZED TRIAL OF ETANIDAZOLE COMBINED WITH RADIOTHERAPY IN HEAD AND NECK CARCINOMAS
From July 1987 to July 1990, 374 patients were randomized in a multicenter trial coordinated by the GustaveRoussy Institute… 
1992
1992
Session C: Concepts and Developments in Cell Sensitization KINETIC UPTAKE OF ETANIDAZOLE IN LUNG CARCINOMA AND NORMAL TISSUE ZZV VZVO
Thirty-four patients affected by primary pulmonary carcinoma or in a state of recurrence after surgery were analyzed and 29/m’ of… 
1990
1990
Bioreductive Drugs and Radiation: Pharmacokinetics and Clinical Trials of Etanidazole Radiosensitizer
One of the biggest problems in recurrence of tumour is the resistance of hypoxic cells1,2. Radiosensitizing drugs, such as… 
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