Etanidazole

Known as: 1H-Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-, 2-Nitroimidazole-1-acetamide, N-(2-hydroxyethyl)-, Etanidazole [Chemical/Ingredient] 
A 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the… (More)
National Institutes of Health

Papers overview

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2007
2007
Paclitaxel and etanidazole are hypoxic radiosensitizers that exhibit cytotoxic action at different mechanisms. The poly(D,L… (More)
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2007
2007
Drug-releasing implants delivering chemotherapeutic and radio-sensitizing agents are beginning to play a major role in the post… (More)
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2002
2002
Etanidazole, a kind of radiosensitizer, was encapsulated in the spray-dried microspheres using biodegradable polymer PLGA 65:35… (More)
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2002
2002
Etanidazole, a hypoxic radiosensitizer, has potential applications in radiotherapy. Due to its high solubility in water, common… (More)
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Highly Cited
1998
Highly Cited
1998
PURPOSE The purpose of the present study is to investigate the strength of association between anemia and overall survival… (More)
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1997
1997
PURPOSE To determine the toxicity and maximum tolerated dose of etanidazole administered concurrently with hyperfractionated… (More)
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Highly Cited
1995
Highly Cited
1995
The present studies were initiated to quantitate the oxygen dependence of bioreductive metabolism-induced binding of EF5, a… (More)
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1994
1994
PURPOSE The objectives of this study were to determine the efficacy and toxicity of Etanidazole (ETA), a hypoxic cell sensitizer… (More)
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Highly Cited
1993
Highly Cited
1993
Hypoxic cells in tissue pose many medical problems, and there is a need for more accurate measurements of tissue hypoxia. However… (More)
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Highly Cited
1990
Highly Cited
1990
In order to investigate the effect of environmentally determined conditions on the cytotoxicity of anticancer treatments, Hoechst… (More)
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