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Etanidazole

Known as: 1H-Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-, 2-Nitroimidazole-1-acetamide, N-(2-hydroxyethyl)-, Etanidazole [Chemical/Ingredient] 
A 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Paclitaxel and etanidazole are hypoxic radiosensitizers that exhibit cytotoxic action at different mechanisms. The poly(D,L… Expand
Highly Cited
2002
Highly Cited
2002
  • F. Wang, Chi-Hwa Wang
  • Journal of controlled release : official journal…
  • 2002
  • Corpus ID: 21408381
Etanidazole, a kind of radiosensitizer, was encapsulated in the spray-dried microspheres using biodegradable polymer PLGA 65:35… Expand
Highly Cited
1998
Highly Cited
1998
PURPOSE The purpose of the present study is to investigate the strength of association between anemia and overall survival… Expand
1997
1997
PURPOSE The aim of the study was to evaluate the efficacy and toxicity of Etanidazole, a hypoxic cell sensitizer, combined with… Expand
Highly Cited
1995
Highly Cited
1995
PURPOSE The objectives of this study were to determine the efficacy and toxicity of Etanidazole (ETA), a hypoxic cell sensitizer… Expand
Highly Cited
1995
Highly Cited
1995
PURPOSE To assess institutional and patient compliance with quality of life (QL) instruments in RTOG clinical trials. To assess… Expand
Highly Cited
1995
Highly Cited
1995
The present studies were initiated to quantitate the oxygen dependence of bioreductive metabolism-induced binding of EF5, a… Expand
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Highly Cited
1994
Highly Cited
1994
Hypoxic modification by nitroimidazoles has been explored in a large number of clinical studies. Nine different drugs… Expand
Highly Cited
1993
Highly Cited
1993
Hypoxic cells in tissue pose many medical problems, and there is a need for more accurate measurements of tissue hypoxia. However… Expand
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Highly Cited
1990
Highly Cited
1990
In order to investigate the effect of environmentally determined conditions on the cytotoxicity of anticancer treatments, Hoechst… Expand
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