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Recurrence patterns after curative resection of colorectal cancer in patients followed for a minimum of ten years.
Surveillance for recurrences, particularly for relapses in the liver and lung, should be performed for at least 4 years in colon cancer patients and patients with rectal cancer should be followed for a longer period. Expand
Preoperative radio/chemo-radiotherapy in combination with intraoperative radiotherapy for T3-4Nx rectal cancer.
The combined preoperative radio/chemo-radiotherapy and IORT for clinical T3-4Nx rectal cancer significantly reduces local recurrence and improves prognosis andCombination of preoperative radiotherapy and oral UFT improves the feasibility of sphincter-preservation. Expand
Prophylactic hepatic arterial infusion chemotherapy for the prevention of liver metastasis in patients with colon carcinoma
5‐fluorouracil (5‐FU) is administered as adjuvant chemotherapy by HAI to patients with colon carcinoma without liver metastases and its effects on recurrence in the liver and survival are studied. Expand
Detection of Carcinoembryonic Antigen Messenger RNA-Expressing Cells in Peripheral Blood 7 Days After Curative Surgery is a Novel Prognostic Factor in Colorectal Cancer
Detection of CEA mRNA expressing cells in peripheral blood 7 days after curative surgery is a novel independent factor predicting recurrence in patients with CRC. Expand
Molecular determinants of folate levels after leucovorin administration in colorectal cancer
The expression level of FPGS, GGH and ABCC1 in CRC tissues could predict the reduced folate level after LV administration, and these factors may determine the efficacy of LV treatment. Expand
Detection of Carcinoembryonic Antigen Messenger RNA–Expressing Cells in Portal and Peripheral Blood During Surgery Does Not Influence Relapse in Colorectal Cancer
The detection of cancer cells in blood taken during surgery is not considered to be a poor-prognostic factor in CRC and the presence of tumor cells in portal or peripheral blood was a factor that reduced recurrence. Expand
Risk of Lymph Node and Distant Metastases in Patients With Early Invasive Colorectal Cancer Classified as Haggitt’s Level 4 Invasion
Although further prospective investigation is required, the positive predictive value increases from 17 to 30 percent when the width of submucosal invasion is added to Haggitt’s Level 4 as an indicator for bowel resection. Expand
Contribution of Indirect Action to Radiation-Induced Mammalian Cell Inactivation: Dependence on Photon Energy and Heavy-Ion LET
The inactivation efficiency for indirect action was greater than that for direct action over the photon energy range and the ion LET range tested, and a significant contribution of direct action was also found for the increased RBE in the low photon energy region. Expand
Detection of tumor cells in the portal and peripheral blood of patients with colorectal carcinoma using competitive reverse transcriptase‐polymerase chain reaction
In spite of many reports, it remains unclear whether the presence of tumor cells in circulating blood flow predicts a poor prognosis.
In vitro and in vivo radiosensitizing effects of 2-nitroimidazole derivatives with sugar component.
In vivo radiosensitization studies in ICR mice with Ehrlich ascites tumor indicated that RK28 produced an increase in DMF to hypoxic tumor cells with increased dose of the compound, which revealed a faster clearance from the serum and a slower decrease in the tumor than with misonidazole. Expand