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SR-2508

Known as: SR 2508, SR2508 
 
National Institutes of Health

Papers overview

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Highly Cited
1987
Highly Cited
1987
Complete pharmacological data from 71 patients treated on the phase I trial of SR 2508 were analyzed to see if the dose-limiting… Expand
  • table 1
  • figure 2
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Highly Cited
1986
Highly Cited
1986
Sixty-five patients were entered on the long schedule of the Phase I trial of SR-2508. The planned total doses ranged from 30 to… Expand
1986
1986
We have recently demonstrated that intracellular elevation of glutathione (GSH) by oxothiazolidine 4-carboxylate lessens SR-2508… Expand
Highly Cited
1984
Highly Cited
1984
  • N. Yu, J. Brown
  • International journal of radiation oncology…
  • 1984
  • Corpus ID: 9726973
Depletion of intracellular glutathione (GSH) can enhance misonidazole (MISO) radiosensitizing efficacy both in vivo and in vitro… Expand
Highly Cited
1984
Highly Cited
1984
From March 15, through August 31, 1983, 37 patients have been entered on the RTOG Phase I trial of SR-2508. The drug was given… Expand
Highly Cited
1984
Highly Cited
1984
  • J. Brown, N. Yu
  • International journal of radiation oncology…
  • 1984
  • Corpus ID: 25310848
We have used the RIF-1 tumor implanted intradermally in the lower dorsum of C3H mice to explore to what extent the… Expand
Highly Cited
1984
Highly Cited
1984
  • J. Brown
  • International journal of radiation oncology…
  • 1984
  • Corpus ID: 38965101
The lack of positive results from the clinical trials undertaken so far with misonidazole (MISO) are widely considered as… Expand
Highly Cited
1981
Highly Cited
1981
Abstract Using a combination of toxicological, pharmacological and radiosensitization experiments on cells in vitro and tumors in… Expand
Highly Cited
1980
Highly Cited
1980
Ten 2-nitroimidazole radiosensitizers of electron affinity equal to that of misonidazole, but differing in their octanol:water… Expand
1980
1980
The behavior of three 2-nitroimidazole drugs of similar electron affinity to misonidazole but with varying octanol: water… Expand