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Radiation-Sensitizing Agents

Known as: Agents, Radiation-Sensitizing, Radiation Sensitizing Drugs, Radiosensitizing Drugs 
Drugs used to potentiate the effectiveness of radiation therapy in destroying unwanted cells.
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (39)

3-aminobenzamide4-nitroacetophenoneAfatinibBromodeoxyuridine

Broader (1)

Pharmaceutical Preparations
RadiationRadiation ToleranceRadiation-Sensitizing EffectStaurosporine

Papers overview

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Review
1991
Review
1991
A therapeutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments.
Review
1989
Review
1989
Sensitization of hypoxic tumour cells--clinical experience.
There is substantial evidence for the presence of hypoxia in human tumours. This is documented by histopathological demonstration… 
Highly Cited
1988
Highly Cited
1988
Enhancement of radiation-induced tumor cell killing by the hypoxic cell toxin SR 4233.
Highly Cited
1983
Highly Cited
1983
Biological response modifiers.
It is clear that the rate of change in biology is rapidly accelerating. This is most apparent in the BRM area with respect to the… 
Highly Cited
1978
Highly Cited
1978
Platinum complexes as radiosensitizers of hypoxic mammalian cells.
Cis-dichlorodiammineplatinum (II), or cis-PDD, has recently been shown to be a potent radiosensitizer of bacteria, particularly… 
Highly Cited
1977
Highly Cited
1977
Cytotoxic effects of the hypoxic cell radiosensitizer Ro 7-0582 to tumor cells in vivo.
The cytotoxicity of the nitroimidazole Ro 7-0582 to tumor cells has been studied in vivo using two transplantable tumors, the… 
Highly Cited
1976
Highly Cited
1976
Oxygen inhibition of nitroreductase: electron transfer from nitro radical-anions to oxygen.
Highly Cited
1975
Highly Cited
1975
Tests of two electron-affinic radiosensitizers in vivo using regrowth of an experimental carcinoma.
Two electron-affinic nitroimidazoles have been investigated as potential radiosensitizers using tumor regrowth as a measure of… 
Highly Cited
1974
Highly Cited
1974
Hypoxic cell radiosensitizers: comparative tests of some electron affinic compounds using epidermal cell survival in vivo.
The ability of certain electron affinic compounds to sensitize hypoxic cells to radiation has been tested using an in vivo assay… 
Highly Cited
1974
Highly Cited
1974
Metronidazole ("Flagyl"). A radiosensitizer of hypoxic cells.
Abstract The radiosensitizing properties of metronidazole have been studied using bacteria, bean roots, and mammalian cells in… 
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