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Since observations from the beginning of the last century, it has become well established that solid tumors may contain oxygen… Expand Two novel heteroleptic sensitizers, Ru((4,4-dicarboxylic acid-2,2'-bipyridine)(4,4'-bis(p-hexyloxystyryl)-2,2-bipyridine)(NCS)2… Expand Poly(ADP-ribose) polymerase-1 (PARP-1) is a member of the PARP enzyme family consisting of PARP-1 and several recently identified… Expand Caffeine exposure sensitizes tumor cells to ionizing radiation and other genotoxic agents. The radiosensitizing effects of… Expand Identification of genetic alterations in bladder cancer is proceeding very rapidly. The most common genetic alteration identified… Expand Members of the phosphatidylinositol-3 kinase related kinase (PIKK) family function in both cell cycle progression and DNA damage… Expand BACKGROUND
Despite notable technical advances in therapy for malignant gliomas during the past decade, improved patient survival… Expand The wide range of tumour pH values that have been determined in human tumours is shown in Fig. 4. It can be seen that tumour pH… Expand The cytotoxicities of a number of antineoplastic agents to oxygenated and hypoxic EMT6 mouse mammary tumor cells in culture were… Expand