Skip to search formSkip to main contentSkip to account menu

Staurosporine

Known as: Staurosporine [Chemical/Ingredient], (9alpha,10beta,11beta,13alpha)-(+)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H-9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, CGP-39360 
A cell permeable alkaloid isolated from Streptomyces staurosporeus exhibiting anti-cancer activity. Staurosporine is a potent, non-selective… 
National Institutes of Health

Related topics

Related topics

31 relations

Narrower (17)

3'-demethoxy-3'-hydroxystaurosporine4'-demethylamino-4'-hydroxystaurosporine5'-hydroxystaurosporine7-O-methyl-UCN 01

Broader (2)

AlkaloidsEnzyme Inhibitors
Antineoplastic AgentsIn BloodNCIt Antineoplastic Agent TerminologyProcess of secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance
Highly Cited
2001
Highly Cited
2001
Gene Expression Profile of Antithrombotic Protein C Defines New Mechanisms Modulating Inflammation and Apoptosis*
Human protein C is a natural anticoagulant factor, and a recombinant activated form of the molecule (rhAPC) is completing… 
Highly Cited
1996
Highly Cited
1996
Small Stress Proteins as Novel Regulators of Apoptosis
Small stress protein expression enhances the survival of mammalian cells exposed to numerous injuries that induce necrotic cell… 
Review
1996
Review
1996
Molecular Mechanisms in Synaptic Vesicle Endocytosis and Recycling
Review
1995
Review
1995
Staurosporine, a potentially important gift from a microorganism.
Discovery of Staurosporine Chemical Properties of Staurosporine A. Structure B. Hydrophobicity C. Binding Domain of Staurosporine… 
Review
1994
Review
1994
The molecular basis for cell cycle delays following ionizing radiation: a review.
Highly Cited
1993
Highly Cited
1993
Activation of endothelial cell phospholipase D by hydrogen peroxide and fatty acid hydroperoxide.
Highly Cited
1992
Highly Cited
1992
A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s)
Highly Cited
1991
Highly Cited
1991
Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components.
Highly Cited
1991
Highly Cited
1991
Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)