Endothelin

Known as: Vasoconstrictor Factors, Endothelium-Derived, Endothelins [Chemical/Ingredient], Endothelins 
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
OBJECTIVES We sought to determine the optimal dose of the selective endothelin A (ET(A)) receptor antagonist sitaxsentan for the… (More)
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Review
2003
Review
2003
Collectively, the endothelins and their receptors — referred to as the endothelin (ET) axis — have key physiological functions in… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND C-reactive protein (CRP) has been suggested to actively participate in the development of atherosclerosis. In the… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Endothelin 1, a powerful endogenous vasoconstrictor and mitogen, might be a cause of pulmonary hypertension. We… (More)
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Highly Cited
1995
Highly Cited
1995
Prostate cancer is the second most common cause of death from cancer in U.S. men, and advanced, hormone–refractory disease is… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND Although recent investigations report the elevation of plasma endothelin (ET) in congestive heart failure (CHF), it… (More)
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Highly Cited
1994
Highly Cited
1994
Endothelin-1 (ET-1), a 21-residue vasoactive peptide, is produced in vascular endothelial cells from the 38-residue inactive… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Endothelin is a family of potent vasoconstrictor peptides of vascular endothelial origin. Although it has been… (More)
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Highly Cited
1990
Highly Cited
1990
This study was designed to examine whether endothelin is released from the intima of intact arteries, and whether endothelium… (More)
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Highly Cited
1988
Highly Cited
1988
An endothelium-derived 21-residue vasoconstrictor peptide, endothelin, has been isolated, and shown to be one of the most potent… (More)
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