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Endothelin-3

Known as: Endothelin 3, Endothelin-3 [Chemical/Ingredient] 
A 21-amino acid peptide that circulates in the plasma, but its source is not known. Endothelin-3 has been found in high concentrations in the brain… 
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (2)

Big Endothelin 3Waardenburg Syndrome, Type 4b
EDN3 geneEndothelin-1Endothelin-2In Blood

Broader (1)

Endothelin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
EndothelinBreceptors are functionally important in mediating vasoconstriction in the systemic circulation in patients with left ventricular systolic dysfunction
Highly Cited
1996
Highly Cited
1996
Role of endothelin in mediating neurogenic plasma extravasation in rat dura mater
Highly Cited
1994
Highly Cited
1994
Human saphenous vein contains both endothelin ETA and ETB contractile receptors.
Highly Cited
1993
Highly Cited
1993
Endothelin receptors in cultured adult rat cardiac fibroblasts.
OBJECTIVES Endothelins, released by vascular endothelial cells, are known growth promoters of various mesenchymal cells that… 
Highly Cited
1993
Highly Cited
1993
Endothelium-dependent regulation of the ophthalmic microcirculation in the perfused porcine eye: role of nitric oxide and endothelins.
PURPOSE The endothelium produces nitric oxide and endothelin (ET). This study was designed to investigate the endothelium… 
Highly Cited
1991
Highly Cited
1991
Endothelin‐3 Regulates Endothelin‐1 Production in Cultured Human Endothelial Cells
Effects of endothelin-3 on the secretion of endothelin-1 and other endothelium-derived substances were investigated in cultured… 
Highly Cited
1991
Highly Cited
1991
Possible neuroendocrine actions of endothelin-3.
The presence of endothelin (ET) immunoreactivity and binding sites in hypothalamus and pituitary gland suggests potential… 
Highly Cited
1991
Highly Cited
1991
Human placenta expresses endothelin gene and corresponding protein is excreted in urine in increasing amounts during normal pregnancy.
Highly Cited
1990
Highly Cited
1990
Regional haemodynamic effects of endothelin‐1 and endothelin‐3 in conscious Long Evans and Brattleboro rats
1 The regional haemodynamic effects of bolus doses (4 and 40 pmol) and infusions (12 and 120 pmol h−1) of endothelin‐1 and… 
Highly Cited
1989
Highly Cited
1989
Studies with Endothelin‐3 and Endothelin‐1 on Rat Blood Pressure and Isolated Tissues: Evidence for Multiple Endothelin Receptor Subtypes
Summary In an anesthetized rat, endothelin-1 (ET-1) causes a rapid, transient fall in blood pressure followed by a large… 
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