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Glaucoma is one of the most common neurodegenerative diseases. Despite this, the earliest stages of this complex disease are… Expand The steroid hormone progesterone (P) plays a pivotal role during ovulation. Mice lacking P receptor (Pgr) gene fail to ovulate… Expand Regardless of proximal cause, photoreceptor injury or disease almost invariably leads to the activation of Muller cells, the… Expand SummaryPlasma concentrations of endothelin, a vasoconstrictor peptide released from vascular endothelial cells, have been… Expand Cardiovascular disease is the leading cause of illness and death in women. Estrogen replacement therapy (ERT) in postmenopausal… Expand Atherosclerosis and hypertension are more common in men than in women, a difference that may be due, in part, to the actions of… Expand By screening a cDNA library derived from the A10 rat vascular smooth muscle cell line for functional expression in COS cells, we… Expand Two distinct cell surface endothelin receptors were identified, namely a 73-kDa protein referred to as ET-R1 and a 60-kDa protein… Expand 1. A radioimmunoassay has been developed for measuring endothelin-like immunoreactivity in human plasma using an antibody raised… Expand We established a highly sensitive and specific sandwich-enzyme immunoassay (EIA) for endothelin-3 (ET-3), which showed no… Expand