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Endothelin-2

Known as: EDN2, Endothelin 2, Endothelin-2 [Chemical/Ingredient] 
Endothelin-2, encoded by the human EDN2 gene, is a macrophage chemoattractant. Endothelins are endothelium-derived vasoconstrictor peptides. The… 
National Institutes of Health

Related topics

Related topics

21 relations
EDN2 geneEDN2 wt AlleleEndothelin-1Endothelin-3

Broader (1)

Endothelin

Narrower (1)

big endothelin 2

Papers overview

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Highly Cited
2002
Highly Cited
2002
Endothelin-2 is a hypoxia-induced autocrine survival factor for breast tumor cells.
Endothelins (ETs) are a group of vasoactive peptides (ET-1, ET-2 and ET-3) produced by many cell types that bind to G-protein… 
Review
2002
Review
2002
New views on the role of endothelin (minireview).
Endothelin was isolated and identified in 1988 by Yanagisawa et al. The endothelin family consists of 21 amino acid isoforms… 
Highly Cited
1998
Highly Cited
1998
A new family of orphan G protein‐coupled receptors predominantly expressed in the brain 1
1995
1995
Regulation of cyclic AMP production in adult human ciliary processes.
Highly Cited
1995
Highly Cited
1995
Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2.
Endothelin (ET)-2 is a 21 residue vasoactive peptide which is biosynthesized from big ET-2(1-38) by a specific cleavage at Trp21… 
1993
1993
Characterization of endothelin isoforms in human heart: endothelin-2 demonstrated.
In humans, three endothelin (ET) isoforms are predicted to exist by analysis of genomic DNA. However, evidence for the presence… 
Highly Cited
1992
Highly Cited
1992
Presence of messenger ribonucleic acid for endothelin-1, endothelin-2, and endothelin-3 in human endometrium and a change in the ratio of ETA and ETB receptor subtype across the menstrual cycle.
The aim of the present study was to determine whether mRNA for the three endothelin peptides (endothelin-1, endothelin-2, and… 
Review
1992
Review
1992
Vasoactive mediators released by endothelins.
Highly Cited
1991
Highly Cited
1991
Human placenta expresses endothelin gene and corresponding protein is excreted in urine in increasing amounts during normal pregnancy.
1991
1991
Immunoreactive endothelin in human plasma, urine, milk, and saliva.
Using a highly sensitive radioimmunoassay, elevated plasma immunoreactive endothelin (ir-ET) levels were found in patients with… 
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