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Endothelin-1

Known as: Endothelin-1 [Chemical/Ingredient], ET-1, Endothelin 1 
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the… 
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
The 21-amino acid peptide endothelin-1 (ET-1) is the predominant isoform of the endothelin peptide family, which includes ET-2… 
Highly Cited
1998
Highly Cited
1998
Endothelial dysfunction associated with atherosclerosis has been attributed to alterations in the L-arginine-nitric oxide (NO… 
Highly Cited
1996
Highly Cited
1996
OCCLUSION of the diseased coronary artery in humans causes acute myocardial infarction, survivors of which have a high risk for… 
Highly Cited
1994
Highly Cited
1994
The endothelin-1 (ET-1) gene was disrupted in mouse embryonic stem cells by homologous recombination to generate mice deficient… 
Highly Cited
1993
Highly Cited
1993
BACKGROUND Pulmonary hypertension is characterized by an increase in vascular tone or an abnormal proliferation of muscle cells… 
Highly Cited
1992
Highly Cited
1992
BackgroundEndothelin is a family of potent vasoconstrictor peptides of vascular endothelial origin. Although it has been proposed… 
Review
1991
Review
1991
OBJECTIVE To explore the role of endothelin-1, a potent endothelial-derived vasoconstrictor peptide, in pulmonary hypertension… 
Highly Cited
1990
Highly Cited
1990
ENDOTHELIN-1 was initially identified as a 21-residue potent vasoconstrictor peptide produced by vascular endothelial cells, but…