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Endothelin-1

Known as: Endothelin-1 [Chemical/Ingredient], ET-1, Endothelin 1 
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the… 
National Institutes of Health

Related topics

Related topics

30 relations

Narrower (6)

Alexa532-endothelin 1Preproendothelin-1Proendothelin (1-38)endothelin-1 (1-21)
Cardiac Hypertrophy PathwayEDN1 geneEndothelin-1 measurementEndothelin-2

Broader (1)

Endothelin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic…
The endothelins are a family of endothelium-derived peptides that possess a variety of functions, including vasoconstriction… 
Highly Cited
2000
Highly Cited
2000
sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development.
Mutation of sucker (suc) disrupts development of the lower jaw and other ventral cartilages in pharyngeal segments of the… 
Review
1994
Review
1994
Growth factors and growth modulators in human uterine endometrium: their potential relevance to reproductive medicine.
Highly Cited
1993
Highly Cited
1993
Endothelin receptors in rat liver: lipocytes as a contractile target for endothelin 1.
The endothelins (ETs) form a group of three vasoactive peptides (ET-1, ET-2, and ET-3) for which two types of cellular receptors… 
Highly Cited
1992
Highly Cited
1992
Polar secretion of endothelin-1 by cultured endothelial cells.
Highly Cited
1991
Highly Cited
1991
Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes.
Highly Cited
1990
Highly Cited
1990
Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veins.
Endothelin-1 is a 21-amino acid endothelial vasoconstrictor peptide that may be the physiological antagonist of endothelium… 
Highly Cited
1990
Highly Cited
1990
Effect of endothelin-1 in man.
The effect of an intravenous infusion of human endothelin-1 on blood pressure and plasma concentrations of endothelin-1… 
Highly Cited
1989
Highly Cited
1989
Abundance of endothelin-3 in rat intestine, pituitary gland and brain.
Highly Cited
1989
Highly Cited
1989
Endothelin 1, an endothelium-derived peptide, is expressed in neurons of the human spinal cord and dorsal root ganglia.
The localization of endothelin 1 mRNA and endothelin-like immunoreactivity was investigated in samples of neurologically normal… 
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