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Endothelin-1

Known as: Endothelin-1 [Chemical/Ingredient], ET-1, Endothelin 1 
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the… 
National Institutes of Health

Related topics

Related topics

30 relations

Narrower (6)

Alexa532-endothelin 1Preproendothelin-1Proendothelin (1-38)endothelin-1 (1-21)
Cardiac Hypertrophy PathwayEDN1 geneEndothelin-1 measurementEndothelin-2

Broader (1)

Endothelin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Attenuation of reperfusion injury by renal ischemic postconditioning: the role of NO.
Highly Cited
2007
Highly Cited
2007
Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with…
Highly Cited
2006
Highly Cited
2006
Endothelin-1 and PKC Induce Positive Inotropy Without Affecting pHi in Ventricular Myocytes
It has been proposed that intracellular alkalinization underlies the enhanced contractility of ventricular myocytes exposed to… 
Highly Cited
2003
Highly Cited
2003
C-reactive protein and atherothrombosis—Beyond a biomarker: an actual partaker of lesion formation
atherosclerosis and its complications represent the most common cause of death in Western societies. Over the past few years we… 
Highly Cited
2001
Highly Cited
2001
Intravenous atrial natriuretic peptide prevents left ventricular remodeling in patients with first anterior acute myocardial infarction.
Highly Cited
1996
Highly Cited
1996
Enhanced Coronary Vasoconstriction to Endothelin-BReceptor Activation in Experimental Congestive Heart Failure
Background Endothelin (ET), a coronary vasoconstrictor, mediates its activity through the specific receptors ET-A and ET-B, which… 
Highly Cited
1994
Highly Cited
1994
Prostaglandin E2 and prostacyclin inhibit the production and secretion of endothelin from cultured endothelial cells.
Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor yet identified. This peptide plays an important role in the… 
Highly Cited
1992
Highly Cited
1992
Endothelin-1 stimulates DNA synthesis and proliferation of pulmonary artery smooth muscle cells.
Endothelin-1 (ET-1), a 21-amino acid peptide released from the endothelium, elicits a variety of biological effects that include… 
Highly Cited
1991
Highly Cited
1991
Endothelin in human brain and pituitary gland: presence of immunoreactive endothelin, endothelin messenger ribonucleic acid, and endothelin receptors.
The presence of immunoreactive (IR) endothelin, endothelin mRNA, and endothelin receptors in human brain and pituitary gland has… 
Highly Cited
1989
Highly Cited
1989
Two distinct types of endothelin receptors are present on chick cardiac membranes.
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