ELANE wt Allele

Known as: HLE, PMN-E, SCN1 
Human ELANE wild-type allele is located in the vicinity of 19p13.3 and is approximately 4 kb in length. This allele, which encodes neutrophil… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Malondialdehyde (MDA), 4-hydroxy-nonenal (HNE) and the F2-isoprostane 15(S)-8-iso-prostaglandin F2α (15(S)-8-iso-PGF2α) are the… (More)
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Review
2007
Review
2007
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are produced in many places in living cells and at an increased… (More)
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Highly Cited
2007
Highly Cited
2007
TRPA1 is an excitatory ion channel expressed by a subpopulation of primary afferent somatosensory neurons that contain substance… (More)
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Review
2006
Review
2006
Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of protein function, which is considered a… (More)
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Review
2002
Review
2002
Amyloid beta-peptide [Abeta(1-42)] is central to the pathogenesis of Alzheimer's disease (AD), and the AD brain is under intense… (More)
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Highly Cited
2001
Highly Cited
2001
Glutamate transporters are involved in the maintenance of synaptic glutamate concentrations. Because of its potential… (More)
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Highly Cited
1999
Highly Cited
1999
In the present study, we studied the signal transduction mechanism that is involved in the expression of c-Jun protein evident… (More)
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Highly Cited
1999
Highly Cited
1999
Reactive oxygen species are involved in a diversity of biological phenomena such as inflammation, carcinogenesis, aging, and… (More)
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Highly Cited
1997
Highly Cited
1997
Recent studies have demonstrated oxidative damage is one of the salient features of Alzheimer's disease (AD). In these studies… (More)
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Highly Cited
1997
Highly Cited
1997
Oxidative stress is believed to play important roles in neuronal cell death associated with many different neurodegenerative… (More)
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