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EIF2C2 wt Allele

Known as: AGO2, Q10, Eukaryotic Translation Initiation Factor 2C, 2 wt Allele 
Human EIF2C2 wild-type allele is located in the vicinity of 8q24 and is approximately 104 kb in length. This allele, which encodes protein argonaute… 
National Institutes of Health

Related topics

Related topics

6 relations
8q24Genetic Translation ProcessRNA DegradationRNA Interference

Broader (1)

AGO2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
microRNA-122 Dependent Binding of Ago2 Protein to Hepatitis C Virus RNA Is Associated with Enhanced RNA Stability and Translation Stimulation
Translation of Hepatitis C Virus (HCV) RNA is directed by an internal ribosome entry site (IRES) in the 5′-untranslated region (5… 
Review
2012
Review
2012
Intracellular localization and routing of miRNA and RNAi pathway components.
Several different pathways, generally termed RNA silencing pathways, utilize small RNA molecules guiding sequence-specific… 
2012
2012
Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing
Small hairpin RNAs (shRNAs) having duplex lengths of 25–29 bp are normally processed by Dicer into short interfering RNAs (siRNAs… 
Highly Cited
2012
Highly Cited
2012
Stem cells and spinal cord repair.
For the past couple of decades, clinicians have watched the stem-cell field with a mixture of anticipation and skepticism. No… 
2012
2012
Expression dynamics of microRNA biogenesis during preimplantation mouse development.
Highly Cited
2011
Highly Cited
2011
Hypomethylation of Intragenic LINE-1 Represses Transcription in Cancer Cells through AGO2
In human cancers, the methylation of long interspersed nuclear element -1 (LINE-1 or L1) retrotransposons is reduced. This occurs… 
Highly Cited
2011
Highly Cited
2011
miRNA profiling along tumour progression in ovarian carcinoma
MicroRNAs (miRNAs) are small non‐coding RNAs that exert a regulatory effect post‐transcriptionally by binding target mRNAs and… 
Review
2009
Review
2009
Argonaute-mediated translational repression (and activation)
microRNAs (miRNAs) down-regulate the expression of their target genes by inducing translational repression and/or mRNA decay… 
Highly Cited
2008
Highly Cited
2008
Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites
RNAi is widely applied to inhibit expression of specific genes, but it is limited by variable efficiency and specificity of… 
1978
1978
M82: the exploding galaxy?
IT is nearly 20 yr since M82 was accepted as the archetypal exploding galaxy. Its most spectacular feature is the system of… 
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