Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer.
Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial.
Randomized intergroup trial of cisplatin-paclitaxel versus cisplatin-cyclophosphamide in women with advanced epithelial ovarian cancer: three-year results.
There is strong and confirmatory evidence from two large randomized phase III trials to support paclitaxel-cisplatin as the new standard regimen for treatment of patients with advanced ovarian cancer.
Snail, Slug, and Smad‐interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
It was demonstrated previously that the Snail family of transcription factors and Smad‐interacting protein 1 (Sip1) regulate E‐cadherin and matrix metalloproteinase 2 (MMP‐2) expression, cellular…
Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial
Epithelial–Mesenchymal Transition in Ovarian Carcinoma
Current knowledge in EMT related to adhesion, transcriptional regulation and chemoresistance, and their clinical relevance are summarized, as well as the recently observed regulation of EMT by microRNA.
Prognostic importance of degree of differentiation and cyst rupture in stage I invasive epithelial ovarian carcinoma
Borderline ovarian tumours.
The prognostic significance of residual disease, FIGO substage, tumor histology, and grade in patients with FIGO stage III ovarian cancer.
Survival was evaluated in 455 patients with FIGO stage III invasive ovarian cancer managed between 1983 and 1991 and the prognostic significance of clinical and histopathological variables was evaluated.