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RNA Interference

Known as: RNA interference (RNAi), Quelling, RNA Silencing 
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or… 
National Institutes of Health

Related topics

Related topics

43 relations
AGO1 geneAGO2 geneAGO3 geneAGO4 gene

Broader (2)

Genetic TechniquesRNA

Narrower (2)

negative regulation of translation involved in RNA interferencesiRNA loading onto RISC involved in RNA interference

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Co-delivery of doxorubicin and RNA using pH-sensitive poly (β-amino ester) nanoparticles for reversal of multidrug resistance of breast cancer.
Highly Cited
2010
Highly Cited
2010
Blockade of Rac1 Activity Induces G1 Cell Cycle Arrest or Apoptosis in Breast Cancer Cells through Downregulation of Cyclin D1, Survivin, and X-Linked Inhibitor of Apoptosis Protein
Rac1 GTPase regulates a variety of signaling pathways that are implicated in malignant phenotypes. Here, we show that selective… 
Highly Cited
2006
Highly Cited
2006
Transgenically expressed viral RNA silencing suppressors interfere with microRNA methylation in Arabidopsis
Highly Cited
2003
Highly Cited
2003
The capacity of transgenic tobacco to send a systemic RNA silencing signal depends on the nature of the inducing transgene locus.
RNA silencing is a conserved eukaryotic pathway in which double-stranded RNA (dsRNA) triggers destruction of homologous target… 
Highly Cited
2003
Highly Cited
2003
RNA interference may be more potent than antisense RNA in human cancer cell lines
1. RNA interference (RNAi) is a newly discovered cellular pathway for the silencing of sequence‐specific genes at the mRNA level… 
Highly Cited
2001
Highly Cited
2001
Further results on interference cancellation and space-time block codes
Space-time block codes (STBC) make use of a rich algebraic structure to provide diversity gains with small decoding complexity… 
Highly Cited
2001
Highly Cited
2001
Role of short RNAs in gene silencing.
Highly Cited
2001
Highly Cited
2001
The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1.
It is well established that acetylation of histone and nonhistone proteins is intimately linked to transcriptional activation… 
Highly Cited
1994
Highly Cited
1994
Performance comparison of a DS/CDMA system using a successive interference cancellation (IC) scheme and a parallel IC scheme under fading
Overcoming near/far effects and fading is imperative for satisfactory performance of DS/CDMA systems. Commercial digital cellular… 
Highly Cited
1994
Highly Cited
1994
Mutational analysis defines a C-terminal tail domain of RAP1 essential for Telomeric silencing in Saccharomyces cerevisiae.
Alleles specifically defective in telomeric silencing were generated by in vitro mutagenesis of the yeast RAP1 gene. The most… 
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