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RNA Interference

Known as: RNA interference (RNAi), Quelling, RNA Silencing 
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or… Expand
National Institutes of Health

Related topics

Related topics

43 relations
AGO1 geneAGO2 geneAGO3 geneAGO4 gene
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Broader (2)

Genetic TechniquesRNA

Narrower (2)

negative regulation of translation involved in RNA interferencesiRNA loading onto RISC involved in RNA interference

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine.
Next-generation DNA sequencing technologies have led to a massive accumulation of genomic and transcriptomic data from patients… Expand
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Review
2018
Review
2018
Exosome Theranostics: Biology and Translational Medicine
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules, such as lipids, proteins, and nucleic acids… Expand
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Review
2017
Review
2017
The Different Mechanisms of Cancer Drug Resistance: A Brief Review
Anticancer drugs resistance is a complex process that arises from altering in the drug targets. Advances in the DNA microarray… Expand
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Review
2017
Review
2017
Principles of Transgenerational Small RNA Inheritance in Caenorhabditis elegans
Examples of transgenerational inheritance of environmental responses are rapidly accumulating. In Caenorhabditis elegans… Expand
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Review
2017
Review
2017
Proteolysis-Targeting Chimeras: Induced Protein Degradation as a Therapeutic Strategy.
Until recently, the only ways to reduce specific protein signaling were to either knock down the target by RNAi or to interfere… Expand
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Review
2017
Review
2017
Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization.
Macrophages become activated initiating innate immune responses. Depending on the signals, macrophages obtain an array of… Expand
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Review
2017
Review
2017
Circular RNA participates in the carcinogenesis and the malignant behavior of cancer.
Circular RNAs (circRNAs) are long, non-coding RNAs that result from the non-canonical splicing of linear pre-mRNAs. However, the… Expand
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Review
2017
Review
2017
RNAi technology: a new platform for crop pest control
The insect pests are big threat in meeting the food demands for future generation. The present pest control strategies, including… Expand
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Review
2017
Review
2017
Next-Generation Lipids in RNA Interference Therapeutics.
RNA is emerging as a potential therapeutic modality for the treatment of incurable diseases. Despite intense research, the advent… Expand
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Highly Cited
2001
Highly Cited
2001
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
RNA interference (RNAi) is the process of sequence-specific, post-transcriptional gene silencing in animals and plants, initiated… Expand
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