AGO2 gene

Known as: EUKARYOTIC TRANSLATION INITIATION FACTOR 2C, SUBUNIT 2, AGO2, argonaute 2 
This gene plays a role in RNA binding and catabolism.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Platelets play a crucial role in the maintenance of hemostasis, as well as in thrombosis. Upon activation, platelets release… (More)
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Highly Cited
2013
Highly Cited
2013
MicroRNAs (miRNAs) are generated by two-step processing to yield small RNAs that negatively regulate target gene expression at… (More)
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Highly Cited
2012
Highly Cited
2012
MicroRNAs (miRNAs) are small noncoding RNAs that regulate eukaryotic gene expression by binding to regions of imperfect… (More)
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Highly Cited
2011
Highly Cited
2011
Synthetic small duplex RNAs that are fully complementary to gene promoters can silence transcription in mammalian cells… (More)
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Highly Cited
2010
Highly Cited
2010
Dicer is a central enzyme in microRNA (miRNA) processing. We identified a Dicer-independent miRNA biogenesis pathway that uses… (More)
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Highly Cited
2009
Highly Cited
2009
In animals, P-bodies or GW-bodies appear to cause the congregation of proteins involved in microRNA (miRNA)-mediated post… (More)
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Highly Cited
2007
Highly Cited
2007
microRNAs (miRNAs) bind to Argonaute (Ago) proteins and inhibit translation or promote degradation of mRNA targets. Human let-7… (More)
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Highly Cited
2005
Highly Cited
2005
MicroRNAs (miRNAs) are generated by a two-step processing pathway to yield RNA molecules of approximately 22 nucleotides that… (More)
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Highly Cited
2004
Highly Cited
2004
Argonaute proteins associate with small RNAs that guide mRNA degradation, translational repression, or a combination of both. The… (More)
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Highly Cited
2004
Highly Cited
2004
In mammalian cells, both microRNAs (miRNAs) and small interfering RNAs (siRNAs) are thought to be loaded into the same RNA… (More)
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